Key takeaways
Ondansetron (Zofran) and dolasetron (Anzemet) are both antiemetic medications used to prevent nausea and vomiting, especially from chemotherapy. Ondansetron (Zofran) is available in multiple forms, including tablets, orally disintegrating tablets, oral solution, and injection, making it versatile for different needs. In contrast, dolasetron (Anzemet) is only available as a tablet, which can be limiting if you have trouble swallowing or keeping medication down. Ondansetron (Zofran) is available as a lower-cost generic, while dolasetron (Anzemet) is only available as a brand-name medication, which can be more expensive. Both medications can cause side effects like headache and fatigue, but ondansetron (Zofran) has a broader range of common side effects, including constipation and diarrhea. Additionally, ondansetron (Zofran) can be used off-label during pregnancy, whereas there isn't enough information to confirm the safety of dolasetron (Anzemet) during pregnancy.
