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Zaditor vs. Azelastine

Zaditor (ketotifen) is an antihistamine eye drop that's available over the counter for allergy-related itchy eyes. It works by blocking histamine and stopping your body from releasing chemicals that cause allergy symptoms. Adults and children can use Zaditor (ketotifen). The typical dosage is one drop into the affected eye(s) twice daily. Side effects can include headache, blurry vision, and dry eyes.

• Allergy-related itchy eyes

• Headache
• Runny nose
• Rash
• Dry eye

• Not to be used with contact lenses
• Allergy to ingredients
• Risk for eye infection

Azelastine nasal spray is an antihistamine that treats allergies and nasal symptoms, such as runny or stuffy nose. The 0.1% and 0.15% strengths of the azelastine nasal spray are available with a prescription for adults and children. It's sprayed into the nostrils typically twice a day. Prescription azelastine nasal spray is a lower-cost generic. Possible side effects include a bitter taste in the mouth and nasal discomfort.

Note: Azelastine 0.15% nasal spray is also available over the counter under the brand name Astepro Allergy.

• Seasonal allergy symptoms related to the nose
• Year-round allergy symptoms related to the nose - azelastine 0.15% spray only
• Runny or stuffy nose that isn't caused by allergies - azelastine 0.1% spray only

Azelastine 0.1% nasal spray:

• Bitter taste in the mouth (20%)
• Headache (15%)
• Sleepiness (12%)
• Nasal burning (4%)

Azelastine 0.15% nasal spray:

• Bitter taste in the mouth (4%)
• Nasal discomfort (4%)

• Possible sleepiness and difficulty concentrating