Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Ubrelvy vs. Nurtec

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ubrelvy (ubrogepant) and Nurtec ODT (rimegepant) are both medications used to treat migraines in adults and belong to the same drug class, calcitonin gene-related peptide (CGRP) receptor blockers. However, they have some differences. Ubrelvy is only approved for treating sudden migraine attacks, while Nurtec ODT is approved for both treating and preventing migraines. Ubrelvy is taken as a regular tablet, with a typical dose of 50 mg to 100 mg, and can be taken up to twice a day. In contrast, Nurtec ODT is a 75 mg orally disintegrating tablet that dissolves on or under your tongue, and is taken once a day as needed for treatment or every other day regularly for prevention. Ubrelvy can cause side effects like nausea, sleepiness, and dry mouth, while Nurtec ODT may cause nausea and stomach pain. Both medications have a lot of drug interactions. Always be sure your pharmacist and prescriber have a complete medication list, including any OTC or herbal supplements you take.

  • Ubrelvy (ubrogepant)
    Nurtec odt (rimegepant)
  • Ubrelvy (ubrogepant)
    Nurtec odt (rimegepant)

  • Summary of Ubrelvy vs. Nurtec

    Summary for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Prescription only

    Ubrelvy (ubrogepant) is a migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It can treat sudden migraine attacks in adults. Ubrelvy (ubrogepant) is a tablet you take by mouth. You take one dose when you feel a migraine starting. If needed, you can take a second dose at least 2 hours later. Your dose depends if Ubrelvy (ubrogepant) interacts with the other medications you take. Side effects include nausea and tiredness.

    Summary for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Prescription only

    Nurtec ODT (rimegepant) is a type of migraine medication called a calcitonin gene-related peptide (CGRP) receptor antagonist. It helps treat migraine attacks with or without aura in adults. It can also help prevent migraines from happening in the long run. This medication is an orally disintegrating tablet (ODT). You put it on or under the tongue and let it dissolve. The dosage is 1 tablet each time. But how often you take the medication depends on if you're taking it to prevent or treat migraines. Side effects include nausea and stomach pain. Nurtec ODT (rimegepant) is a brand-name medication; there's no generic version yet.

  • Indications of Ubrelvy vs. Nurtec

    Indications for
    •Treatment of migraine attacks with or without aura in adults
    Indications for
    •Treatment of migraines with or without aura in adults
    •Prevention of migraines with or without aura in adults

  • Pros and Cons of Ubrelvy vs. Nurtec

    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Pros
    •A tablet that's taken by mouth
    •Helps treat sudden migraine attacks
    •Good option when triptans like sumatriptan (Imitrex) haven't worked well
    Cons
    •Takes 1 to 2 hours to start working
    •Not for preventing migraines
    •Can interact with other medications, like verapamil and phenobarbital
    Pros and Const for Calcitonin gene-related peptide (CGRP) receptor antagonist
    Pros
    •A first-choice option for preventing migraines
    •Generally has fewer side effects than triptans
    •Can take without any foods or liquids
    •Dissolves on the tongue, so it's a good option for people who don't like to or can't swallow pills
    Cons
    •Usually a second-choice option for treating migraines (after trying triptans)
    •Can interact with certain medications, like some antifungals and antiseizure medications
    •Might not be the best choice if you have serious liver or kidney problems
    •Not approved for children (but studies are ongoing)

  • Common Side Effects of Ubrelvy vs. Nurtec

    Common Side Effects for
    •Nausea (up to 4%)
    •Sleepiness (up to 3%)
    •Dry mouth (up to 2%)
    Common Side Effects for
    •Nausea (up to 3%)
    •Stomach pain or indigestion (up to 2%)

  • Warnings of Ubrelvy vs. Nurtec

    Common Side Effects for
    •Allergic reactions
    •High blood pressure
    •Raynaud's phenomenon
    Common Side Effects for
    •Allergic reactions
    •High blood pressure
    •Raynaud's phenomenon

  • Prices with our coupons for Ubrelvy vs. Nurtec

    Learn more about Ubrelvy
    Learn more about Nurtec odt

Compare other Migraine drugs

Emgality vs UbrelvyQulipta vs UbrelvyReyvow vs UbrelvyUbrelvy vs AimovigUbrelvy vs AjovyUbrelvy vs NurtecUbrelvy vs RelpaxUbrelvy vs RizatriptanUbrelvy vs ZolmitriptanAimovig vs AjovyAimovig vs BotoxAimovig vs EmgalityAjovy vs EmgalityEmgality vs NurtecFioricet vs RelpaxFiorinal vs RelpaxImitrex vs RelpaxMaxalt vs RelpaxNurtec vs AimovigNurtec vs RizatriptanNurtec vs SumatriptanQulipta vs AimovigQulipta vs NurtecRelpax vs AmergeRelpax vs AxertRelpax vs CafergotRelpax vs ErgotamineReyvow vs AjovyReyvow vs MaxaltReyvow vs Zecuity
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.