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Ryaltris vs. Dymista

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Ryaltris

(olopatadine / mometasone)

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Dymista

(azelastine / fluticasone)

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Summary for Ryaltris

Prescription only

Ryaltris is a combination of two medications: olopatadine (an antihistamine) and mometasone (a corticosteroid). It's a nasal spray used to treat eye and nasal symptoms of seasonal allergies (e.g., runny nose, stuffy nose, sneezing, itchy eyes) in people ages 12 and older. The dosage is 2 sprays in each nostril twice per day. Ryaltris (olopatadine / mometasone) doesn't have a generic version since it's only available as a brand-name medication. Side effects aren't common, but include a bad taste in the mouth and nosebleeds.

Indications for Ryaltris

  • Eye and nasal symptoms of seasonal allergies (e.g., runny nose, stuffy nose, sneezing, itchy eyes)

Pros and Cons for Ryaltris

Pros

  • Combines two first-choice medications into a single spray
  • Starts to work within 15 minutes
  • Less side effects than antihistamines and steroids taken by mouth

Cons

  • Can cause nosebleeds and nasal irritation
  • Need to use twice per day
  • Available by prescription only

Common Side Effects for Ryaltris

Warnings for Ryaltris

  • Nasal problems
  • Drowsiness
  • Eye and vision problems
  • Allergic reactions
  • Risk of infection
  • Altered stress hormone levels
  • Slowed growth in children

Summary for Dymista

Prescription only

Dymista is a combination nasal spray containing azelastine (an antihistamine) and fluticasone (a corticosteroid). It's used by people ages 6 years and older to treat nasal allergy symptoms, such as runny, stuffy, or itchy nose. The typical dose is to spray one spray into each nostril twice per day. Side effects aren't common, but include headache and a bad taste in the mouth. Dymista (azelastine / fluticasone) is available as both brand-name and generic medications.

Indications for Dymista

  • Nasal allergy symptoms (e.g., runny, stuffy, or itchy nose, sneezing, itchy or watery eyes)

Pros and Cons for Dymista

Pros

  • Combines two medications into a single spray
  • Starts to work within 30 minutes after the first dose
  • Likely safe to use during pregnancy

Cons

  • Prescription only
  • Need to use daily for 2 weeks to experience the full effects of fluticasone in Dymista
  • Need to use twice per day

Common Side Effects for Dymista

Warnings for Dymista

  • Sleepiness
  • Nose bleeds, discomfort, and injury
  • Risk of infection
  • Altered stress hormone levels
  • Delayed growth in children
  • Allergic reactions
  • Eye and vision problems

Prices with our coupons for Ryaltris vs. Dymista

Price Card Drug Icon
Ryaltris1 nasal spray / 240 metered sprays of 665mcg/25mcg/spray
$45.52$299.23
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Price Card Drug Icon
Azelastine/Fluticasone1 nasal spray / 23g of 137mcg/50mcg
$47.39$155.12
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