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Renova vs. Tretinoin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Renova and Retin-A are both topical forms of tretinoin, but they have different FDA-approved uses. Renova is specifically approved to lessen the appearance of fine facial wrinkles, while Retin-A is approved to treat acne in individuals ages 12 and older. Both medications are applied once daily, typically in the evening, and can cause similar side effects , such as skin irritation, redness, and peeling. Both medications can make your skin more sensitive to sunlight, and Retin-A may initially worsen acne before improvement is seen. Neither medication is recommended for use during pregnancy due to potential risks to the unborn baby.

Renova

(tretinoin)

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Retin-A

(tretinoin)

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Summary for Renova

Prescription only

Renova is a topical retinoid that contains tretinoin 0.02% cream. Renova (tretinoin) can ease fine facial wrinkles, in addition to the regular use of sunscreen and sun-protective clothing. But it won't help get rid of deep wrinkles or hyperpigmentation from years of sun damage. Renova (tretinoin) is applied to the face once daily in the evening. This medication commonly causes skin irritation and peeling as side effects. Renova is a prescription medication that's brand name only and not available as a generic.

Indications for Renova

Pros and Cons for Renova

Pros

  • Applied only once a day
  • Only need a small pearl-sized amount to have an effect
  • Can use with other cosmetics or skincare products (must wait at least 1 hour after applying Renova)

Cons

  • Doesn't get rid of deep wrinkles, repair sun-damaged skin, reverse skin aging due to sun damage, or make skin younger
  • Can make you sunburn more easily
  • Not a good choice for females who want to become pregnant or are pregnant

Common Side Effects for Renova

Almost all people who used Renova in clinical studies reported one or more of the following:

  • Burning or stinging
  • Peeling
  • Redness
  • Dry skin
  • Itching

Warnings for Renova

  • Skin irritation
  • Sunburns
  • Harm to unborn baby

Summary for Tretinoin

Prescription only

Retin-A (tretinoin) is a retinoid medication that's used to treat acne in adults and children 12 years and older. It's available as a cream or a gel that's applied onto the skin once a day. Side effects include skin irritation, redness, and peeling. Your acne might get worse at the beginning of treatment, but it should get better as you continue using the medication. You must have a prescription for Retin-A (tretinoin) from your primary care provider or dermatologist; this medication isn't available over the counter.

Indications for Tretinoin

  • Acne

Pros and Cons for Tretinoin

Pros

  • Easy to apply onto your skin
  • Only need to apply once nightly
  • Available in a lower-cost generic form

Cons

  • Makes your skin more sensitive to sunlight, which can lead to sunburns
  • Can cause your skin color to temporarily become lighter or darker
  • Might worsen your acne during the first few weeks of treatment

Common Side Effects for Tretinoin

  • Skin peeling or discomfort
  • Warm feeling or stinging after applying
  • Skin redness
  • Sensitivity to sunlight (sunburns)
  • Worsening of acne in the first few weeks of treatment

Warnings for Tretinoin

  • Sunburns
  • Skin irritation in extreme weather
  • Skin reactions

Prices with our coupons for Renova vs. Tretinoin

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Refissa1 tube / 20g of 0.05%
$72.10$153.92
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Tretinoin1 tube / 45g of 0.025%
$38.37$287.44
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