Key takeaways
Oxycodone (Oxycontin, Roxicodone) is a prescription medication that treats severe pain that isn't relieved by non-opioid pain medications. Acetaminophen / codeine (Tylenol #3) also contains an opioid, but it’s prescribed for mild-to-moderate pain. All opioids are controlled substances and have side effects such as sleepiness, dizziness, and constipation. More seriously, they can lead to misuse and overdose. However, these serious risks are more likely with oxycodone than they are with acetaminophen / codeine.
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