Skip to main content
HomeDrug Comparisons
Drug bottle and Pill

Compare Cyclobenzaprine vs. Gabapentin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Cyclobenzaprine
    Gabapentin (Neurontin)
  • Cyclobenzaprine
    Gabapentin (Neurontin)

  • Summary of Cyclobenzaprine vs. Gabapentin

    Summary for Muscle relaxant
    Prescription only

    Cyclobenzaprine is a muscle relaxant used in addition to rest and physical therapy to treat muscle pain and discomfort. It's available as an immediate-release (IR) tablet and an extended-release (ER) capsule. Unlike other muscle relaxants, it's not considered a controlled substance. Cyclobenzaprine can make you sleepy as a side effect so it's best to avoid alcohol to prevent serious harm from combining the two together.

    Summary for Antiepileptic
    Prescription only

    Gabapentin (Neurontin) is a medication approved to treat certain seizures and nerve pain. It's typically taken 3 times daily by mouth, and is available as pills and a liquid. Common side effects include dizziness and sleepiness.

  • Indications of Cyclobenzaprine vs. Gabapentin

    Indications for
    •Muscle discomfort caused by acute (not long-term) conditions
    Indications for
    •Nerve pain from shingles in adults
    •Add on treatment for partial (focal) seizures in people age 3 years and older

  • Pros and Cons of Cyclobenzaprine vs. Gabapentin

    Pros and Const for Muscle relaxant
    Pros
    •Works well to relieve muscle spasms
    •Available as an IR tablet and ER capsule
    •Available as a lower-cost generic
    •Can use if you have kidney problems
    Cons
    •Can make you feel dizzy and sleepy
    •Only meant for short-term use (up to 2 to 3 weeks)
    •Doesn't work for muscle spasms caused by brain or spinal injuries
    •Might not be a good option if you're 65 years or older or have liver problems because of higher risk of side effects
    Pros and Const for Antiepileptic
    Pros
    •Works well for seizures and nerve pain
    •Available as a lower-cost generic
    •Available as a tablet, capsule, and liquid for those who have trouble swallowing pills
    •Dose can be adjusted based on response
    Cons
    •Needs to be taken multiple times per day
    •Stopping the medication suddenly can lead to serious problems, such as seizures
    •Can raise your risk of suicidal thoughts or behavior
    •Commonly causes dizziness

  • Common Side Effects of Cyclobenzaprine vs. Gabapentin

    Common Side Effects for

    Immediate-release tablets:

    •Drowsiness (up to 39%)
    •Dry mouth (up to 32%)
    •Dizziness (up to 11%)
    •Feeling tired (up to 6%)
    •Headache (up to 5%)

    Extended-release capsules:

    •Dry mouth (6-14%)
    •Dizziness (3-6%)
    •Indigestion (up to 4%)
    •Nausea (3%)
    •Feeling tired (3%)
    •Constipation (1-3%)
    •Drowsiness (1-2%)
    Common Side Effects for
    •Dizziness (17-28%)
    •Sleepiness (19-21%)
    •Poor muscle control/clumsiness (3-13%)
    •Fatigue (3-11%)

  • Warnings of Cyclobenzaprine vs. Gabapentin

    Common Side Effects for
    •Serotonin syndrome
    •Effect on driving and concentration
    •Dry mouth, dry eyes, and trouble urinating
    •Caution use in people with liver problems
    Common Side Effects for
    •Severe allergic and skin reactions
    •Difficulty concentrating, extreme sleepiness, and dizziness
    •Withdrawal problems
    •Suicidal thoughts or behavior
    •Dangerously slow breathing (respiratory depression)
    •Brain and mental health side effects in children

  • Prices with our coupons for Cyclobenzaprine vs. Gabapentin

    Learn more about Cyclobenzaprine
    Learn more about Gabapentin

Compare other Musculoskeletal Conditions and Epilepsy drugs

Carisoprodol vs CyclobenzaprineCyclobenzaprine vs GabapentinCyclobenzaprine vs MeloxicamCyclobenzaprine vs OxycodoneCyclobenzaprine vs Tramadol
View More

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.