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Acetaminophen / Codeine Coupon - Acetaminophen / Codeine 300mg/30mg tablet

acetaminophen / codeine

Generic Tylenol With Codeine
Used for Pain
Used for Pain

Tylenol with Codeine (acetaminophen / codeine), also known as Tylenol #3, is a combination opioid medication. Both acetaminophen and codeine treat mild-to-moderate pain by blocking pain signals in the body. This medication is taken by mouth, typically every 4 hours as needed. Tylenol with Codeine is available as a tablet and liquid. Like other opioids, Tylenol with Codeine can cause common side effects like sleepiness, dizziness, and constipation. It also has a warning for dangerous breathing problems and risk of dependence and misuse.

Last reviewed on April 2, 2024
Tylenol with Codeine is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.
basics-icon

What is Tylenol with Codeine?

What is Tylenol with Codeine used for?

How Tylenol with Codeine works

Tylenol with Codeine is a combination of two medications that work together to treat pain.

Are you looking for information on codeine instead?
When does Tylenol with Codeine start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsTylenol #3 (brand no longer available)
Drug ClassAnalgesic / Opioid
Controlled Substance ClassificationSchedule III
Generic StatusLower-cost generic available
AvailabilityPrescription only
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$16.77(save 63.23%)
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$6.17
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What are the risks and warnings for Tylenol with Codeine?

Tylenol with Codeine can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

risk-warning

Potential for dependence and misuse

  • Risk factors: History of alcohol or substance misuse | Taking more Tylenol with Codeine than prescribed | Suddenly stopping Tylenol with Codeine

    Even at recommended doses, taking Tylenol with Codeine can put a person at risk for addiction, abuse, or misuse. Taking Tylenol with Codeine for reasons other than prescribed (misuse) or at higher doses than prescribed can lead to overdose and death. Your healthcare professional (HCP) will prescribe the lowest amount of Tylenol with Codeine that's necessary for the shortest period of time possible.

    The FDA requires a Risk Evaluation and Mitigation Strategies (REMS) program for this medication because of its potential for dependence and misuse. Under the REMS program, your HCP will go over how to use Tylenol with Codeine safely, its risks, and proper storage and disposal to help keep you and your loved ones safe. If you have concerns about taking Tylenol with Codeine, talk to your HCP about alternative pain medications.

    risk-warning

    Dangerously slow breathing (respiratory depression)

    • Risk factors: Older adult | Children younger than 12 years old | Taking medications that can cause slow breathing | Drinking alcohol | Medical conditions that cause breathing problems | Taking higher doses of Tylenol with Codeine | Ultra-rapid metabolizers of Tylenol with Codeine | Breastfed babies from mothers taking Tylenol with Codeine

      Tylenol with Codeine can cause dangerously slow breathing, which can be life-threatening. This can happen at any time, but you're at higher risk 1 to 3 days right after you start Tylenol with Codeine or right after your HCP raises your dose. Drinking alcohol and taking other medications, like benzodiazepines, can also raise your risk for this dangerous side effect. You're recommended to ask your prescriber about getting naloxone (Narcan) before you start Tylenol with Codeine so that you can have it available in case of an accidental overdose. If you or your loved one notice you have trouble breathing or have bluish-colored lips, fingers, or toes, call 911 to get medical help right away.

      risk-warning

      Risk of accidental overdose

      • Risk factors: History of opioid use disorder | Previous opioid overdose | Taking high doses of Tylenol with Codeine | Taking more opioids than prescribed | Alcohol use | Age 65 years or older


        Take Tylenol with Codeine exactly as prescribed. Taking too much Tylenol with Codeine or taking it more often than prescribed can lead to an overdose. If you're taking the liquid version of this medication, make sure to use a medication dosing cup or oral syringe to measure out your dose. Don't use a household spoon because the dose might not be accurate and you might accidentally take too much medication. Be sure you and your loved ones know how to recognize symptoms of an overdose, such as not responding to sound or touch, extremely slowed breathing, extreme sleepiness, slow heartbeat, and cold or clammy skin.

        Your HCP will likely prescribe naloxone (Narcan) for you to have on hand in case of an accidental opioid overdose. Make sure you carry naloxone (Narcan) with you at all times in case you experience an overdose. Call 911 right away if this happens.

        Store Tylenol with Codeine out of reach from children, pets, or visitors. If you don't need to take Tylenol with Codeine anymore, throw away the medication through a take-back program.

        risk-warning

        Harm to newborn babies

        If you take Tylenol with Codeine during pregnancy, you can pass the medication to your unborn baby. Long-term use during pregnancy can cause your unborn baby to become dependent on opioids. Once your baby is born, they can experience withdrawal symptoms, such as high-pitched crying, poor feeding and sucking behavior, trembling, irritability, abnormal sleep patterns, and seizures. This condition is called neonatal opioid withdrawal syndrome and can be life-threatening if not recognized and treated in time. Let your healthcare provider know if you've used Tylenol with Codeine during pregnancy or if you notice these symptoms in your baby.

        risk-warning

        Serious medication interactions

        Tylenol with Codeine can interact with many medications. For example, taking certain medications, like erythromycin (Ery-tab) and ritonavir (Norvir), can raise the level of codeine and put you at higher risk for breathing problems. And starting certain medications, like rifampin (Rifadin) or carbamazepine (Tegretol), while you're already taking Tylenol with Codeine might lower the level of codeine and put you at risk for withdrawal symptoms.

        Before starting Tylenol with Codeine, make sure your care team is aware of all the medications you're currently taking. Don't start or stop any medications without first checking with your care team.

        risk-warning

        Difficulty concentrating and extreme sleepiness

        • Risk factors: Taking higher doses of Tylenol with Codeine | Age 65 years or older | Drinking alcohol | Taking other medications that can cause sleepiness

          Tylenol with Codeine can cause extreme sleepiness and lower your ability to think, react, and focus. Your risk is higher if you're taking other medications that can make you sleepy, such as benzodiazepines, muscle relaxants, and sleep medications. Make sure you know how this medication affects you before driving a car or doing activities that require your concentration. Talk to your HCP right away if you feel too sleepy from taking Tylenol with Codeine.

          risk-warning

          Liver damage

          • Risk factors: Drinking alcohol | Taking other medications containing acetaminophen | Taking higher than recommended dose of acetaminophen | Liver problems

            Taking too much acetaminophen can cause liver damage that can be permanent and life-threatening. For adults, the maximum amount of acetaminophen is 3,000 mg or 4,000 mg, depending on your health condition, in a 24-hour period, depending on your prescriber's instructions. For children, ask your child's pediatrician.

            Speak to your provider before using Tylenol with Codeine if you have liver problems, since it can cause further damage to your liver. Also avoid drinking alcohol while taking Tylenol with Codeine, since this combination can harm your liver too.

            Signs of liver problems include dark urine, feeling tired, upset stomach or stomach pain, or yellowing of the skin or whites of the eyes. If you notice any of these symptoms, call your HCP right away.

            risk-warning

            Severe allergic and skin reactions

            • Risk factors: Allergy to other opioids | Sulfite allergy

              Severe allergic reactions to Tylenol with Codeine are possible, including life-threatening reactions like facial swelling, shock, and anaphylaxis (e.g., closing of the throat). If you notice hives, rash, red skin, swelling of the lips or tongue, or difficulty breathing after taking Tylenol with Codeine, get medical attention right away.

              Additionally, although rare, acetaminophen can cause serious skin reactions, such as rash, blisters, skin reddening, or skin peeling. If you notice changes in your skin, stop using Tylenol with Codeine and get medical attention right away.

              risk-warning

              Seizures

              • Risk factors: History of seizure conditions

                Opioids can cause people with a history of seizures to have seizures more often. Tylenol with Codeine can also raise your risk of seizures in certain situations. Let your HCP know if you have seizures more often while taking Tylenol with Codeine.

                risk-warning

                Low blood pressure

                Tylenol with Codeine can cause extremely low blood pressure, including a drop in blood pressure when you stand from a sitting or lying down position. This can lead to dizziness and fainting. To avoid falling, get up slowly if you've been sitting or lying down. If dizziness or lightheadedness doesn't go away, talk to your HCP.

                risk-warning

                Low adrenal hormone levels

                • Risk factors: Taking Tylenol with Codeine for longer than 1 month

                  Though rare, opioids like Tylenol with Codeine can cause your adrenal hormone levels to drop. This is more likely to happen after taking opioids for longer than 1 month. Symptoms include nausea, vomiting, not feeling hungry, tiredness, dizziness, and weakness. Let your provider know right away if you experience these symptoms because you might need to stop Tylenol with Codeine and be treated with corticosteroids.

                  risk-warning

                  Caution in certain medical conditions

                  People with certain medical conditions shouldn't take Tylenol with Codeine.

                  For example, this medication can't be taken by people with certain stomach-related conditions, such as slow movement of the gut. The codeine in this medication can worsen gut movement.

                  Tylenol with Codeine isn't appropriate for people with head injuries, brain tumors, or other brain-related medical conditions. This is because this medication can slow breathing and lower oxygen levels in the brain, which can be dangerous.

                  Before starting Tylenol with Codeine, make sure to let your medical team know about what medical conditions you have so that they can check to see if this medication is safe for you to take.

                  risk-warning

                  Withdrawal

                  If you have been taking Tylenol with Codeine every day for an extended period of time, don't suddenly stop taking this medication without talking with your HCP. Stopping this medication too suddenly can lead to opioid withdrawal, which includes symptoms such as anxiety, nausea, diarrhea, and stomach pain

                  basics-icon

                  What are the side effects of Tylenol with Codeine?

                  The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

                  Common Side Effects

                  • Drowsiness
                  • Lightheadedness
                  • Dizziness
                  • Sleepiness
                  • Trouble breathing
                  • Nausea
                  • Vomiting
                  • Constipation
                  • Sweating

                  Other Side Effects

                  • Changes in mood
                  • Stomach pain
                  • Rash
                  • Itchy skin

                  Serious Side Effects

                  Contact your healthcare provider immediately if you experience any of the following.
                  • Opioid overdose: not responding to sound or touch, slowed breathing, extreme sleepiness, slow heartbeat, small pupils the size of a pinhead, cold or clammy skin, pain on the upper right side of the stomach, dark urine, yellowing of your skin or eyes
                  • Opioid withdrawal: anxiety, suicidal thoughts, restlessness, runny nose, yawning, sweating, chills, wide pupils, irritability
                  • Dangerously slow breathing: trouble breathing, bluish-colored lips, fingers, or toes
                  • Serious allergic and skin reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing, skin reddening, blisters, rash
                  When do Tylenol with Codeine possible side effects begin and end?
                  Time passed since treatment started:
                  MINUTES
                  HOURS
                  DAYS
                  WEEKS
                  MONTHS
                  Drowsiness
                  Nausea and vomiting
                  Constipation
                  Trouble breathing
                  Seek immediate medical care if you experience this side effect.
                  If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

                  Source: DailyMed

                  The following side effects have also been reported

                  Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

                  Check with your doctor immediately if any of the following side effects occur:

                  More common

                  Difficult or trouble breathing

                  irregular, fast or slow, or shallow breathing

                  pale or blue lips, fingernails, or skin

                  Incidence not known

                  Black, tarry stools

                  bleeding gums

                  blood in the urine or stools

                  cough

                  difficulty with swallowing

                  dizziness

                  fast heartbeat

                  fever with or without chills

                  general feeling of tiredness or weakness

                  hives, itching, skin rash

                  hoarseness

                  lower back or side pain

                  painful or difficult urination

                  pinpoint red spots on the skin

                  puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

                  sore throat

                  sores, ulcers, or white spots on the lips or in the mouth

                  tightness in the chest

                  unusual bleeding or bruising

                  unusual tiredness or weakness

                  Get emergency help immediately if any of the following symptoms of overdose occur:

                  Symptoms of overdose

                  Bloody or cloudy urine

                  chills

                  constricted, pinpoint, or small pupils (black part of the eye)

                  dark urine

                  headache

                  increased sweating

                  light-colored stools

                  loss of appetite

                  loss of consciousness

                  nausea

                  seizures

                  stomach pain

                  sudden decrease in the amount of urine

                  unpleasant breath odor

                  vomiting

                  vomiting of blood

                  yellow eyes or skin

                  Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

                  More common

                  Drowsiness

                  lightheadedness

                  relaxed and calm feeling

                  sleepiness

                  Incidence not known

                  Difficulty having a bowel movement

                  false or unusual sense of well-being

                  Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

                  Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

                  pros-and-cons

                  Pros and cons of Tylenol with Codeine

                  thumbs-up

                  Pros

                  Works well for treating mild-to-moderate pain

                  Combines 2 medications with different modes of pain relief into a single pill

                  Available in a liquid form for people who have trouble swallowing tablets

                  Available as a generic medication

                  thumbs-down

                  Cons

                  For short-term pain relief only

                  Can be habit-forming

                  Not recommended to take with other medications containing acetaminophen, since it can raise the risk of liver damage

                  Liquid solution contains alcohol

                  pharmacist-tips

                  Pharmacist tips for Tylenol with Codeine

                  pharmacist
                  • You can take Tylenol with Codeine with or without food. If it's upsetting your stomach, try taking it with food to help.

                    • Avoid drinking alcohol while taking opioid-containing medications, like Tylenol with Codeine. Drinking alcohol can worsen certain side effects of Tylenol with Codeine, such as sleepiness and dizziness. It can also harm your ability to think or react, as well as raise your risk for dangerously slow breathing.

                      • If you've been taking Tylenol with Codeine regularly for a period of time and want to stop, talk with your provider first. They might need to lower your dose slowly over time before you can stop completely. This is to help you avoid withdrawal symptoms, such as anxiety, sweating, chills, and irritability.

                        • If you're taking the liquid form, store the medication at room temperature. Make sure to only use a medication dose cup or syringe from the pharmacy to measure out your dose. Don't use household spoons because they aren't accurate and might cause you to take too much Tylenol with Codeine.

                          • Ask your pain specialist about getting naloxone (Narcan). This is a medication that's used to help reverse the effects of Tylenol with Codeine during an accidental overdose. You're recommended to have this medication with you, as a precaution.

                            • Let your prescriber know if you're pregnant before you start taking Tylenol with Codeine or if you become pregnant while you're taking this medication. Tylenol with Codeine isn't recommended during pregnancy.

                              • Tell your healthcare team if you're breastfeeding. It's typically recommended to avoid Tylenol with Codeine because the opioid medication can get into breast milk. This raises the risk for serious side effects to your baby (e.g., sleepiness, slowed breathing).

                                • Keep Tylenol with Codeine out of reach from children, pets, or visitors. There are a few drug take-back options to get rid of the medication safely if you don't need to take it anymore. This lessens the risk for accidental overdose and medication misuse.

                                  faqs

                                  Frequently asked questions about Tylenol with Codeine

                                  Is Tylenol with Codeine a narcotic?
                                  Yes, Tylenol with Codeine (acetaminophen / codeine) is considered a narcotic because it contains codeine, an opioid pain medication.
                                  Is Tylenol with Codeine habit-forming?
                                  Yes, Tylenol with Codeine (acetaminophen / codeine) has a black box warning for risk for addiction and dependence. It's schedule III controlled substance. To lower the risk for addiction, your pain specialist will prescribe the lowest dose of Tylenol with Codeine for the shortest period of time needed to treat your pain.
                                  Does Tylenol with Codeine make you sleepy?
                                  Tylenol with Codeine (acetaminophen / codeine) can make you sleepy as a side effect. The risk is higher if you're taking other medications that make you sleepy, such as certain allergy medications or antidepressants. Make sure to avoid driving or doing anything that requires concentration until you know how this Tylenol with Codeine affects you. If this medication makes you feel too sleepy to get through your day, talk with your pain specialist. They can help you find a different medication to treat pain.
                                  Does Tylenol with Codeine cause constipation?
                                  Yes, constipation is a well-known side effect of opioid-containing medications, like Tylenol with Codeine (acetaminophen / codeine). To prevent constipation, make sure to drink plenty of water and add more fiber-rich foods into your diet. If that doesn't work, ask your pain specialist if it's appropriate for you to take over-the-counter constipation medications, like senna (Senokot, Ex-Lax) or bisacodyl tablets (Dulcolax, Gentle Laxative).
                                  Can I buy Tylenol with Codeine over the counter?
                                  No, Tylenol with Codeine (acetaminophen / codeine) is only available by prescription. But acetaminophen (Tylenol) as a single ingredient without codeine is available over the counter.
                                  Can I take ibuprofen (Advil) with Tylenol with Codeine?
                                  If you need more pain relief, you might be able to take a non-steroidal anti-inflammatory drug NSAIDs like ibuprofen (Advil) or naproxen (Aleve), along with Tylenol with Codeine (acetaminophen / codeine). NSAIDs don't directly interact with Tylenol with Codeine because they work differently to relieve pain. But ask your pain specialist before you start any NSAIDs because they're not appropriate for people with certain medical conditions, such as heart problems or kidney problems.
                                  Can I take Tylenol with Codeine while pregnant?
                                  Tylenol with Codeine (acetaminophen / codeine) isn't recommended during pregnancy because codeine is an opioid. According to the CDC, taking opioid medications during pregnancy raises the risk for birth defects and complications at birth. Additionally, your baby can become dependent on opioids and develop neonatal abstinence syndrome after being born. This is a serious and sometimes life-threatening condition where the baby is born with opioid withdrawal symptoms, such as high-pitched crying, poor feeding and sucking behavior, vomiting, and seizures. If you're pregnant or thinking of becoming pregnant, ask your pain specialist about safer options for pain relief in pregnancy.
                                  What's the difference between Tylenol with Codeine #1, #2, #3, and #4?
                                  Tylenol with Codeine #1, #2, #3, and #4 were brand name medications of Tylenol with Codeine that have since been discontinued. They all contained the same amount of acetaminophen, but had different dosages of codeine. Tylenol #1 contained 7.5 mg of codeine, Tylenol #2 contained 15 mg of codeine, Tylenol #3 contained 30 mg of codeine, and Tylenol #4 contained 60 mg of codeine. While these brand name medications have been discontinued, there are similar generic versions available.
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                                  dosage

                                  Tylenol with Codeine dosage forms

                                  The average cost for 12 tablets of 300mg/30mg of Tylenol with Codeine is $6.17 with a free GoodRx coupon. This is 63.23% off the average retail price of $16.77.
                                  ml of oral solution
                                  Ml of oral solution
                                  DosageQuantityPrice as low asPrice per unit
                                  120mg/12mg/5ml120 ml$14.10$0.12
                                  tablet
                                  Tablet
                                  DosageQuantityPrice as low asPrice per unit
                                  300mg/15mg20 tablets$6.50$0.33
                                  300mg/30mg12 tablets$6.17$0.51
                                  300mg/60mg120 tablets$35.86$0.30

                                  Typical dosing for Tylenol with Codeine

                                  Your healthcare professional (HCP) will prescribe the lowest dose of Tylenol with Codeine for the shortest duration of time to treat your pain.

                                  Tylenol with Codeine tablets

                                  • Adults: The typical starting dose is 300 mg/15 mg (Tylenol with Codeine) by mouth every 4 hours as needed for pain.

                                  Tylenol with Codeine oral solution
                                  Each 5 mL contains 12 mg of codeine and 120 mg of acetaminophen.

                                  • Adults: The typical dose is 15 mL by mouth every 4 hours as needed.

                                  Don't take more than 4,000 mg of acetaminophen within a 24-hour period.

                                  Tylenol with Codeine shouldn't be given to children younger than 12 years of age, or to children younger than 18 years of age if they recently had tonsil or adenoid surgery.

                                  Reviews

                                  Tylenol with Codeine Reviews

                                  GoodRx has partnered with PatientsLikeMe to provide reviews on the different aspects of Tylenol with Codeine.

                                  Effectiveness

                                  Learn more about the effectiveness of Tylenol with Codeine based on real life experiences.

                                  Overall Rating

                                  Based on 52 people taking this medication

                                  3.2

                                  Effectiveness by condition:

                                  fibromyalgia39 reviews

                                  3.2

                                  obsessive-compulsive disorder5 reviews

                                  3.3

                                  migraine4 reviews

                                  3.8

                                  chronic pain syndrome2 reviews

                                  2.5

                                  degenerative disc disease2 reviews

                                  3.1

                                  Side effects
                                  Learn more about the side effects others have reported while taking Tylenol with Codeine.

                                  Severity of side effects

                                  Based on 182 people taking this medication

                                  None

                                  38%

                                  Mild

                                  30%

                                  Moderate

                                  25%

                                  Severe

                                  9%

                                  0%

                                  50%

                                  100%

                                  Top side effects

                                  Based on 182 people taking this medication

                                  Constipation

                                  14%

                                  Sleepiness

                                  5%

                                  Nausea

                                  5%

                                  Upset stomach

                                  3%

                                  Headaches

                                  3%

                                  Usage
                                  Review why people stop taking this medication and how long they take it.

                                  Reasons people stopped taking Tylenol with Codeine

                                  Based on 188 people who have taken this medication

                                  Did not seem to work

                                  25%

                                  Doctor's advice

                                  20%

                                  Course of treatment ended

                                  19%

                                  Side effects too severe

                                  18%

                                  Other

                                  16%

                                  Personal research

                                  3%

                                  Change in health plan coverage

                                  2%

                                  Powered by:Patients Like Me logo
                                  interactions

                                  Interactions between Tylenol with Codeine and other drugs

                                  Tylenol with Codeine may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Tylenol with Codeine. Please note that only the generic name of each medication is listed below.

                                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                  Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                  drug-cost

                                  How much does Tylenol with Codeine cost?

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                                  contraindications-icon

                                  Tylenol with Codeine contraindications

                                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Tylenol with Codeine will not be safe for you to take.
                                  • Children younger than 12 years of age

                                  • Children younger than 18 years of age for pain management after tonsil or adenoid surgery

                                  • Severely slowed breathing (respiratory depression)

                                  • Severe asthma

                                  • Conditions that cause blockage of the stomach passageway

                                  • Allergy to codeine or another opioid

                                  • Allergy to acetaminophen (Tylenol)

                                  • Current or recent (within 14 days) use of a monoamine oxidase inhibitor MAOIs

                                  alternatives

                                  What are alternatives to Tylenol with Codeine?

                                  There are a number of medications that your doctor can prescribe in place of Tylenol with Codeine. Compare a few possible alternatives below.
                                  Tylenol with Codeine
                                  Used for:
                                  $6.17 Lowest GoodRx priceView Prices
                                  Used for:
                                  $12.06 Lowest GoodRx priceView Prices
                                  images

                                  Tylenol with Codeine images

                                  White Round 3 And M - Acetaminophen / Codeine Phosphate 300mg-30mg Tablet
                                  This medicine is White, Round Tablet Imprinted With "M" And "3".White Round 3 And M - Acetaminophen / Codeine Phosphate 300mg-30mg Tablet
                                  White Round U36 - Acetaminophen / Codeine Phosphate 300mg-30mg Tablet
                                  This medicine is White, Round Tablet Imprinted With "U36".White Round U36 - Acetaminophen / Codeine Phosphate 300mg-30mg Tablet
                                  White Round 3 And Ip 33 - Acetaminophen / Codeine Phosphate 300mg-30mg Tablet
                                  This medicine is White, Round Tablet Imprinted With "3" And "Ip 33".White Round 3 And Ip 33 - Acetaminophen / Codeine Phosphate 300mg-30mg Tablet

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                                  References

                                  Best studies we found

                                  Centers for Disease Control and Prevention. (2022). About opioid use during pregnancy

                                  Department of Justice, Drug Enforcement Administration. (2020). Narcotics.

                                  Drugs and Lactation Database (LactMed®). (2023). Codeine.

                                  View All References (13)

                                  Food and Drug Administration. (2023). Opioid analgesic Risk Evaluation and Mitigation Strategy (REMS).

                                  Food and Drug Administration. (2022). Drug disposal: Drug take back locations.

                                  Food and Drug Administration. (2016). FDA drug safety communication: FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen.

                                  Food and Drug Administration. (2015). Determination that TYLENOL WITH CODEINE (acetaminophen with codeine phosphate) oral tablets, 325 milligrams/7.5 milligrams, 325 milligrams/15 milligrams, 325 milligrams/30 milligrams, and 325 milligrams/60 milligrams, were not withdrawn from sale for reasons of safety or effectiveness. Federal Register.

                                  Genus Lifesciences Inc. (2023). ACETAMINOPHEN AND CODEINE PHOSPHATE solution [package insert]. DailyMed.

                                  Gerriets, V., et al. (2022). Acetaminophen. StatPearls.

                                  Jansson, L. M., et al. (2020). Neonatal abstinence syndrome. Pediatric Clinics of North America.

                                  National Institute of Diabetes and Digestive and Kidney Diseases. (n.d.). Adrenal insufficiency & Addison’s disease.

                                  National Institute of Diabetes and Digestive and Kidney Diseases. (2018). Symptoms & causes of adrenal insufficiency & Addison’s Disease.

                                  Opioid Analgesics REMS Program Companies. (n.d.). Risk evaluation and mitigation strategy (REMS).

                                  SpecGx LLC. (2023). ACETAMINOPHEN AND CODEINE PHOSPHATE tablet [package insert]. DailyMed.

                                  Takahashi, P. Y., et al. (2017). Increased risk of hospitalization for ultrarapid metabolizers of cytochrome P450 2D6. Pharmacogenomics and Personalized Medicine.

                                  U.S. Department of Health and Human Services. (n.d.). Preventing an opioid overdose.

                                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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