Key takeaways
Nasonex (mometasone) and Nyquil Cold and Flu (acetaminophen/dextromethorphan/doxylamine) are both used to treat symptoms related to respiratory issues, but they work in different ways and are used for different conditions. Nasonex is a corticosteroid nasal spray that helps reduce inflammation and treat allergy symptoms like a stuffy or runny nose, sneezing, and itchy nose. It is available both over-the-counter and by prescription. On the other hand, Nyquil Cold and Flu is a combination of an analgesic, a cough suppressant, and an antihistamine, used to relieve cold and flu symptoms such as cough, sore throat, fever, and minor aches. Nyquil is only available over-the-counter and can make you feel sleepy due to the antihistamine doxylamine. Nasonex does not cause drowsiness and is used regularly to prevent symptoms, while Nyquil is taken as needed for short-term relief. Additionally, Nasonex is safe for children as young as 2 years old (OTC version), whereas Nyquil should not be used in children under 12 years old.
