Skip to main content

Compare
Nasonex vs. Advil Allergy and Congestion

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nasonex (mometasone) and Advil Allergy and Congestion Relief (ibuprofen/phenylephrine/chlorpheniramine) are both used to treat allergy symptoms, but they work in different ways and are used for different purposes. Nasonex is a corticosteroid nasal spray that reduces inflammation in the nose and is available both over-the-counter and by prescription. It is used to prevent and treat seasonal allergies and nasal polyps. On the other hand, Advil Allergy and Congestion Relief is a combination of an antihistamine, an NSAID, and a decongestant, and is taken orally. It provides short-term relief for a variety of symptoms from allergies and the common cold, such as runny nose, sneezing, and sinus pressure. Nasonex is suitable for children as young as 2 years old (OTC version), while Advil Allergy and Congestion Relief is only for those 12 and older. Nasonex can take 1 to 2 weeks to show full effects, whereas Advil Allergy and Congestion Relief works more quickly but needs to be taken every 4 hours. Additionally, Nasonex does not cause drowsiness, while Advil Allergy and Congestion Relief can make you sleepy and dizzy.

mometasone nasal spray

 

Get free coupons

Advil Allergy and Congestion Relief

 

Get free coupons

Summary for Nasonex

Prescription or over-the-counter

Mometasone nasal spray is used to prevent the nose symptoms of seasonal allergies, as well as to treat nose and sinus inflammation in adults with nasal polyps. Some side effects this medication can cause include headache and bloody nose. Mometasone nasal spray is available both with a prescription and over the counter (OTC).

Indications for Nasonex

  • Temporary relief of allergy symptoms (e.g., stuffy or runny nose, sneezing, itchy nose) (OTC only)
  • Prevention of seasonal allergies (prescription only)
  • Treatment of long-term nose and sinus inflammation with nasal polyps (prescription only)

Pros and Cons for Nasonex

Pros

  • Works well to prevent and treat allergy symptoms
  • Available OTC
  • Can be used to help control allergy symptoms in children 2 years or older (OTC only)
  • Available as a lower-cost generic with a prescription

Cons

  • Can take 1 to 2 weeks or longer to see the full effects
  • Doesn't have a counter on the spray bottle, so it can be hard to remember how many sprays are left
  • Can cause side effects like headache and nose bleeds in some people
  • Unknown if safe while pregnant or breastfeeding

Common Side Effects for Nasonex

  • Headache (26%)
  • Viral infection (14%)
  • Sore throat (12%)
  • Bloody nose or mucus (11%)
  • Coughing (7%)
  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Period cramps (5%)
  • Muscle pain (5%)
  • Congestion, pressure near the nose or forehead, and other symptoms of sinus infection (5%)

Warnings for Nasonex

  • Nose injury and slowed wound healing
  • Fungal infection in the nose and throat
  • Vision changes
  • Risk of infection
  • Hormone changes
  • Poor growth in children

Summary for Advil Allergy and Congestion

Over-the-counter

Advil Allergy and Congestion Relief is a combination of three medications, chlorpheniramine (antihistamine), ibuprofen (non-steroidal anti-inflammatory drug (NSAID)), and phenylephrine (decongestant). It's available over the counter (OTC) and used to treat symptoms from allergies and the common cold.

Indications for Advil Allergy and Congestion

  • Short-term relief of symptoms from allergies and the common cold: runny nose, itchy or watery eyes, itchy nose or throat, sneezing, nasal congestion, sinus pressure, headache, minor aches and pains, fever
  • Lowers swelling in the sinuses around the nose
  • Restores breathing through the nose

Pros and Cons for Advil Allergy and Congestion

Pros

  • Can treat a wide variety of allergy and common cold symptoms
  • More convenient to take three medications in one pill
  • Available over the counter

Cons

  • Needs to be taken every 4 hours
  • More difficult to customize the dose since Advil Allergy and Congestion Relief is a combination of three medications
  • Can cause stomach bleeding or stomach ulcers
  • Can't be used in children younger than 12 years old, right before or after heart surgery, or with current or recent (within the last 14 days) use of monoamine oxidase inhibitors (MAOIs)

Common Side Effects for Advil Allergy and Congestion

  • Dizziness
  • Sleepiness
  • Constipation
  • Upset stomach
  • Heartburn
  • Nausea
  • Headache
  • Dry mouth

Warnings for Advil Allergy and Congestion

  • Stomach bleeding
  • Heart attack and stroke
  • Severe allergic reactions
  • Worsening of medical conditions
  • Accidental overdose
  • Potential harm to unborn baby

Prices with our coupons for Nasonex vs. Advil Allergy and Congestion

Price Card Drug Icon
Mometasone1 nasal spray / 17g of 50mcg
$39.19$136.12
Get free coupons
More Information
Price Card Drug Icon
Advil Allergy And Congestion10 tablets / 200mg/10mg/4mg
$12.26-
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.