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Compare Nasonex vs. Astepro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nasonex (mometasone) and Astepro (azelastine) are both nasal sprays used to treat allergy symptoms, but they work differently and have some key differences. Nasonex is a corticosteroid that reduces inflammation and is available both over-the-counter (OTC) and by prescription. It can be used for relief of allergy symptoms, prevention of seasonal allergies, and treatment of nasal polyps. Astepro, on the other hand, is an antihistamine that blocks histamine to relieve symptoms like a stuffy or runny nose, sneezing, and itching. Astepro is available OTC and is not a steroid. Nasonex can be used by children as young as 2 years old for OTC use, while Astepro is only approved for children 6 years and older. Nasonex may take 1 to 2 weeks to show full effects, whereas Astepro can start working within 15 to 30 minutes. Additionally, Nasonex does not cause drowsiness, but Astepro might make you feel sleepy. Both medications have side effects, but they differ in type and frequency.

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  • Mometasone nasal spray
    Astepro allergy (azelastine)
  • Mometasone nasal spray
    Astepro allergy (azelastine)

  • Summary of Nasonex vs. Astepro

    Summary for Corticosteroid

    Mometasone nasal spray is used to prevent the nose symptoms of seasonal allergies, as well as to treat nose and sinus inflammation in adults with nasal polyps. Some side effects this medication can cause include headache and bloody nose. Mometasone nasal spray is available both with a prescription and over the counter (OTC).

    Summary for Antihistamine

    Astepro Allergy (azelastine) is an antihistamine nasal spray that's used to treat nasal symptoms due to allergies, such as stuffy nose, sneezing, and runny nose. Astepro Allergy (azelastine) is available over-the-counter (OTC) for adults and children 6 years and older. The strength of Astepro Allergy (azelastine) is 0.15%. The dosage depends on your age, but it's usually sprayed into the nose once or twice a day. Side effects can include a bitter taste in the mouth, nasal discomfort, and sneezing. <br/> Note: Azelastine nasal spray is also available by prescription in 0.1% and 0.15% strengths.

  • Indications of Nasonex vs. Astepro

    Indications for
    •Temporary relief of allergy symptoms (e.g., stuffy or runny nose, sneezing, itchy nose) (OTC only)
    •Prevention of seasonal allergies (prescription only)
    •Treatment of long-term nose and sinus inflammation with nasal polyps (prescription only)
    Indications for

    Short-term relief of nasal symptoms due to allergies:

    •Stuffy nose
    •Runny nose
    •Sneezing
    •Itchy nose

  • Pros and Cons of Nasonex vs. Astepro

    Pros and Const for Corticosteroid
    Pros
    •Works well to prevent and treat allergy symptoms
    •Available OTC
    •Can be used to help control allergy symptoms in children 2 years or older (OTC only)
    •Available as a lower-cost generic with a prescription
    Cons
    •Can take 1 to 2 weeks or longer to see the full effects
    •Doesn't have a counter on the spray bottle, so it can be hard to remember how many sprays are left
    •Can cause side effects like headache and nose bleeds in some people
    •Unknown if safe while pregnant or breastfeeding
    Pros and Const for Antihistamine
    Pros
    •Available over the counter; doesn't require a prescription
    •Sprayed directly in the nose
    •Can work within 15 to 30 minutes to relieve allergy symptoms
    Cons
    •Not approved for children younger than 6 years old
    •Can cause drowsiness
    •Might leave a bitter taste in your mouth

  • Common Side Effects of Nasonex vs. Astepro

    Common Side Effects for
    •Headache (26%)
    •Viral infection (14%)
    •Sore throat (12%)
    •Bloody nose or mucus (11%)
    •Coughing (7%)
    •Upper respiratory tract infection (i.e., common cold; 6%)
    •Period cramps (5%)
    •Muscle pain (5%)
    •Congestion, pressure near the nose or forehead, and other symptoms of sinus infection (5%)
    Common Side Effects for
    •Bitter taste (up to 6%)
    •Nasal discomfort (up to 4%)
    •Nosebleed (up to 2%)
    •Sneezing (up to 2%)

  • Warnings of Nasonex vs. Astepro

    Common Side Effects for
    •Nose injury and slowed wound healing
    •Fungal infection in the nose and throat
    •Vision changes
    •Risk of infection
    •Hormone changes
    •Poor growth in children
    Common Side Effects for
    •Possible sleepiness and difficulty concentrating

  • Prices with our coupons for Nasonex vs. Astepro

    Learn more about Mometasone nasal spray
    Learn more about Astepro allergy

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