Key takeaways
Nasonex (mometasone) and Astepro (azelastine) are both nasal sprays used to treat allergy symptoms, but they work differently and have some key differences. Nasonex is a corticosteroid that reduces inflammation and is available both over-the-counter (OTC) and by prescription. It can be used for relief of allergy symptoms, prevention of seasonal allergies, and treatment of nasal polyps. Astepro, on the other hand, is an antihistamine that blocks histamine to relieve symptoms like a stuffy or runny nose, sneezing, and itching. Astepro is available OTC and is not a steroid. Nasonex can be used by children as young as 2 years old for OTC use, while Astepro is only approved for children 6 years and older. Nasonex may take 1 to 2 weeks to show full effects, whereas Astepro can start working within 15 to 30 minutes. Additionally, Nasonex does not cause drowsiness, but Astepro might make you feel sleepy. Both medications have side effects, but they differ in type and frequency.
