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Phenylephrine vs. Nasonex

Head-to-head comparisons of medication uses, side effects, warnings, and more.

phenylephrine eye drops

 

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mometasone nasal spray

 

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Summary for Phenylephrine

Prescription only

Phenylephrine eye drops are used to dilate (widen) pupils for eye exams or certain eye procedures. Side effects include temporary burning or stinging in the eye, blurry vision, and possibly raise your blood pressure. Let your provider know if your pregnant or breastfeeding because you might need to use a different medication.

Indications for Phenylephrine

  • Dilate (widen) pupils

Pros and Cons for Phenylephrine

Pros

  • Can be used in adults and children
  • Starts working quickly (within 15 minutes)
  • Available as a lower-cost generic medication

Cons

  • Can cause eye pain and stinging
  • Dilating effects can last for up to 7 hours (or longer)
  • The 10% strength can raise blood pressure in people with certain heart or thyroid problems

Common Side Effects for Phenylephrine

  • Temporary stinging or burning in your eye
  • Temporary blurry vision
  • Sensitivity to light

Warnings for Phenylephrine

  • For use in the eyes only
  • Heart problems
  • High blood pressure
  • Rebound pupil constriction

Summary for Nasonex

Prescription or over-the-counter

Mometasone nasal spray is used to prevent the nose symptoms of seasonal allergies, as well as to treat nose and sinus inflammation in adults with nasal polyps. Some side effects this medication can cause include headache and bloody nose. Mometasone nasal spray is available both with a prescription and over the counter (OTC).

Indications for Nasonex

  • Temporary relief of allergy symptoms (e.g., stuffy or runny nose, sneezing, itchy nose) (OTC only)
  • Prevention of seasonal allergies (prescription only)
  • Treatment of long-term nose and sinus inflammation with nasal polyps (prescription only)

Pros and Cons for Nasonex

Pros

  • Works well to prevent and treat allergy symptoms
  • Available OTC
  • Can be used to help control allergy symptoms in children 2 years or older (OTC only)
  • Available as a lower-cost generic with a prescription

Cons

  • Can take 1 to 2 weeks or longer to see the full effects
  • Doesn't have a counter on the spray bottle, so it can be hard to remember how many sprays are left
  • Can cause side effects like headache and nose bleeds in some people
  • Unknown if safe while pregnant or breastfeeding

Common Side Effects for Nasonex

  • Headache (26%)
  • Viral infection (14%)
  • Sore throat (12%)
  • Bloody nose or mucus (11%)
  • Coughing (7%)
  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Period cramps (5%)
  • Muscle pain (5%)
  • Congestion, pressure near the nose or forehead, and other symptoms of sinus infection (5%)

Warnings for Nasonex

  • Nose injury and slowed wound healing
  • Fungal infection in the nose and throat
  • Vision changes
  • Risk of infection
  • Hormone changes
  • Poor growth in children

Prices with our coupons for Phenylephrine vs. Nasonex

Price Card Drug Icon
Phenylephrine1 eye dropper / 2ml of 2.5%
$21.67$40.99
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Price Card Drug Icon
Mometasone1 nasal spray / 17g of 50mcg
$39.19$136.12
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