Key takeaways
Phenylephrine eye drops and Nyquil Cold and Flu (acetaminophen/dextromethorphan/doxylamine) are used for different purposes and have distinct characteristics. Phenylephrine is a prescription eye drop used to dilate pupils for eye exams or procedures, while Nyquil Cold and Flu is an oral medication used to relieve symptoms of the common cold and flu, such as cough, sore throat, and fever. Nyquil Cold and Flu is available over-the-counter and combines three medications: a pain reliever, a cough suppressant, and an antihistamine. Phenylephrine can cause side effects like temporary eye stinging and increased blood pressure, while Nyquil Cold and Flu can make you sleepy and dizzy. Additionally, phenylephrine is used in both adults and children for eye dilation, but Nyquil Cold and Flu should not be used in children under 4 years old. Both medications have generic options available.
