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Compare Mounjaro vs. Trulicity

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Mounjaro (tirzepatide)
    Trulicity (dulaglutide)
  • Mounjaro (tirzepatide)
    Trulicity (dulaglutide)

  • Summary of Mounjaro vs. Trulicity

    Summary for GIP and GLP-1 agonist
    Prescription only

    Mounjaro (tirzepatide) is a prescription injection used to improve blood sugar control in people 10 years and older with Type 2 diabetes. It works best when you also follow a nutritious diet and exercise regularly. Mounjaro (tirzepatide) belongs to the drug class called GIP and GLP-1 agonists. The dosage is convenient because it's injected under the skin once a week. Some common side effects of Mounjaro (tirzepatide) include nausea and diarrhea. It can also lower your appetite, which might lead to some weight loss.

    Summary for GLP-1 agonist
    Prescription only

    Trulicity (dulaglutide) is a glucagon-like peptide-1 (GLP-1) agonist that helps control blood sugar in people 10 years and older with Type 2 diabetes. It's also approved to lower the risk of heart problems like heart attacks, strokes, and heart-related death in certain adults with Type 2 diabetes. The medication is injected under the skin once a week. Common side effects include nausea, vomiting, diarrhea, and stomach pain. When taken with certain diabetes medications like insulin, there's a higher risk of low blood sugar (hypoglycemia).

  • Indications of Mounjaro vs. Trulicity

    Indications for
    •Type 2 diabetes in adults and children 10 years of age and older
    Indications for
    •Manage Type 2 diabetes in people 10 years and older, along with diet and exercise
    •Lower the risk of heart problems like heart attack, stroke, or death in adults with Type 2 diabetes who have heart disease or heart-related risk factors

  • Pros and Cons of Mounjaro vs. Trulicity

    Pros and Const for GIP and GLP-1 agonist
    Pros
    •Given once weekly
    •Can lower A1C by an average of up to 2.3% in about 9 months
    •Comes in vials and ready-to-use injectable pens
    •Can use if you have liver or kidney problems
    Cons
    •Only available as an injection given under the skin
    •Can cause unpleasant side effects like nausea, vomiting, and diarrhea
    •Takes time to reach a dose that works well
    •Might not be safe during pregnancy
    Pros and Const for GLP-1 agonist
    Pros
    •Works well at lowering A1C
    •Comes as a ready-to-use injectable pen
    •Only used once a week
    •Helps with weight loss
    Cons
    •Commonly causes nausea, vomiting, diarrhea, and stomach pain
    •Potential risk for thyroid tumors
    •Can cause problems in the pancreas, kidney, and gallbladder
    •Not recommended for people with stomach problems

  • Common Side Effects of Mounjaro vs. Trulicity

    Common Side Effects for
    •Nausea (12-18%)
    •Diarrhea (12-17%)
    •Low appetite (5-11%)
    •Vomiting (5-9%)
    •Indigestion (5-8%)
    •Constipation (6-7%)
    •Stomach pain (5-6%)
    Common Side Effects for
    •Nausea (12-21%)
    •Diarrhea (7-13%)
    •Vomiting (6-13%)
    •Stomach pain (7-9%)
    •Low appetite (5-9%)
    •Fatigue (4-6%)
    •Indigestion (3-6%)

  • Warnings of Mounjaro vs. Trulicity

    Common Side Effects for
    •Risk of thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Low blood sugar (hypoglycemia) when used with other diabetes medications
    •Allergic reactions
    •Stomach side effects
    •Kidney damage due to dehydration
    •Eye problems in people with diabetic retinopathy
    •Gallbladder problems
    •Lung problems during general anesthesia or deep sedation
    Common Side Effects for
    •Thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Low blood sugar when used with certain diabetes medications
    •Severe allergic reactions
    •Kidney damage
    •Severe stomach-related side effects
    •Worsening eye problems in people with diabetic retinopathy
    •Gallbladder problems
    •Breathing fluid into your lungs during anesthesia or deep sedation

  • Prices with our coupons for Mounjaro vs. Trulicity

    Learn more about Mounjaro
    Learn more about Trulicity

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