Mounjaro vs. Trulicity for Diabetes Type 2 and Management with Incretin-based Therapies: Important Differences and Potential Risks.

Mounjaro

(tirzepatide)

Trulicity

(dulaglutide)

Summary for Mounjaro

Prescription only

Mounjaro (tirzepatide) is a prescription injection used to improve blood sugar control in people 10 years and older with Type 2 diabetes. It works best when you also follow a nutritious diet and exercise regularly. Mounjaro (tirzepatide) belongs to the drug class called GIP and GLP-1 agonists. The dosage is convenient because it's injected under the skin once a week. Some common side effects of Mounjaro (tirzepatide) include nausea and diarrhea. It can also lower your appetite, which might lead to some weight loss.

Indications for Mounjaro

Type 2 diabetes in adults and children 10 years of age and older

Pros and Cons for Mounjaro

Pros

Given once weekly
Can lower A1C by an average of up to 2.3% in about 9 months
Has different forms some people can choose from (vials, single-dose injectable pens, multi-dose KwikPens)
Can use if you have liver or kidney problems

Cons

Must give as an injection given under the skin
Can cause unpleasant side effects like nausea, vomiting, and diarrhea
Takes time to reach a dose that works well
Might not be safe during pregnancy

Common Side Effects for Mounjaro

Nausea (12-18%)
Diarrhea (12-17%)
Low appetite (5-11%)
Vomiting (5-9%)
Indigestion (5-8%)
Constipation (6-7%)
Stomach pain (5-6%)

Warnings for Mounjaro

Risk of thyroid cancer
Inflammation of the pancreas (pancreatitis)
Low blood sugar (hypoglycemia) when used with other diabetes medications
Allergic reactions
Stomach side effects
Kidney damage due to dehydration
Eye problems in people with diabetic retinopathy
Gallbladder problems
Lung problems during general anesthesia or deep sedation
Don't share Mounjaro KwikPens with anyone

Summary for Trulicity

Prescription only

Trulicity (dulaglutide) is a glucagon-like peptide-1 (GLP-1) agonist that helps improve blood sugar levels for adults and children with Type 2 diabetes when used along with diet and exercise. It's also approved to lower the risk of heart problems like heart attack, stroke, and heart-related death in certain adults with Type 2 diabetes. The medication comes as a pen that's injected under the skin once a week. Common side effects include nausea, vomiting, diarrhea, and stomach pain.

Indications for Trulicity

Type 2 diabetes in people 10 years and older, along with diet and exercise
Lower the risk of heart problems, like heart attack, stroke, or death, in adults with Type 2 diabetes who have heart disease or heart-related risk factors

Pros and Cons for Trulicity

Pros

Works well at lowering A1C
Comes as a ready-to-use injectable pen
Only used once a week
Helps with weight loss

Cons

Commonly causes nausea, vomiting, diarrhea, and stomach pain
Potential risk for thyroid tumors
Can cause problems in the pancreas, kidney, and gallbladder
Not recommended for people with stomach problems

Common Side Effects for Trulicity

Nausea (12-21%)
Diarrhea (7-13%)
Vomiting (6-13%)
Stomach pain (7-9%)
Low appetite (5-9%)
Fatigue (4-6%)
Indigestion (3-6%)

Warnings for Trulicity

Thyroid cancer
Inflammation of the pancreas (pancreatitis)
Low blood sugar when used with certain diabetes medications
Severe allergic reactions
Kidney damage
Severe stomach-related side effects
Worsening eye problems in people with diabetic retinopathy
Gallbladder problems
Breathing fluid into your lungs during anesthesia or deep sedation

Prices with our coupons for Mounjaro vs. Trulicity

Mounjaro1 carton / 4 pens of 2.5mg/0.5ml

$1,087.84$1,667.57

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Trulicity1 carton / 4 pens of 0.75mg/0.5ml

$985.69$1,509.99

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Mounjaro vs. Trulicity

Mounjaro

Trulicity

Summary for Mounjaro

Indications for Mounjaro

Pros and Cons for Mounjaro

Pros

Cons

Common Side Effects for Mounjaro

Warnings for Mounjaro

Summary for Trulicity

Indications for Trulicity

Pros and Cons for Trulicity

Pros

Cons

Common Side Effects for Trulicity

Warnings for Trulicity

Prices with our coupons for Mounjaro vs. Trulicity

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Mounjaro

Trulicity

Summary for Mounjaro

Indications for Mounjaro

Pros and Cons for Mounjaro

Pros

Cons

Common Side Effects for Mounjaro

Warnings for Mounjaro

Summary for Trulicity

Indications for Trulicity

Pros and Cons for Trulicity

Pros

Cons

Common Side Effects for Trulicity

Warnings for Trulicity