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Lidoderm vs. Methyl salicylate

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lidoderm (lidocaine 5% patch) and methyl salicylate are both topical medications used to relieve pain, but they belong to different medication classes. Lidoderm is a prescription patch that's FDA-approved for treating nerve pain from shingles, known as postherpetic neuralgia. It works by numbing the nerves in the skin. Methyl salicylate, on the other hand, is a topical analgesic available over-the-counter and is used for minor aches and pains in muscles and joints, such as those from arthritis or sprains. Lidoderm is applied as a 5% patch that you wear for up to 12 hours in a 24-hour period, while methyl salicylate comes in various forms like patches, creams, and ointments, and can be applied multiple times a day. Lidoderm is prescription-only, whereas methyl salicylate is available without a prescription. Common side effects of Lidoderm include skin irritation and redness, while methyl salicylate may cause a burning sensation. Both medications should not be applied to damaged skin, and you should avoid using heat over the application area to prevent absorbing too much medication.

Lidocaine 5% patch

(Lidoderm)

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methyl salicylate

 

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Summary for Lidoderm

Prescription only

Lidocaine 5% patch (Lidoderm) is a prescription medication used to relieve nerve pain caused by a shingles infection, also called postherpetic neuralgia (PHN). It's a local anesthetic that works by numbing your nerves to help reduce pain. You apply the patch directly to the painful area of your skin once a day, and it can be worn for up to 12 hours in a 24-hour period. Common side effects include temporary skin irritation, redness, and a mild burning sensation where the patch is applied.

Indications for Lidoderm

Pros and Cons for Lidoderm

Pros

  • Works directly on the skin
  • Generally well-tolerated with few side effects
  • Can cut patches to fit the area of pain

Cons

  • Commonly causes skin irritation
  • Must avoid contact with water wearing the patch
  • Might interact with many medications

Common Side Effects for Lidoderm

  • Blisters
  • Bruising
  • Burning sensation
  • Changes in skin color
  • Rash or redness
  • Swelling
  • Peeling or flaking skin
  • Itching
  • Small bumps or spots
  • Tiny red or purple dots under the skin
  • Tingling or numbness in the area

Warnings for Lidoderm

  • Blood problem (methemoglobinemia)
  • Absorbing too much medication
  • Accidental poisoning in children or pets

Summary for Methyl salicylate

Over-the-counter

Methyl salicylate is a topical counter-irritant that makes the skin less sensitive to pain so it's used to help relieve minor aches and pains. It's available as an over-the-counter (OTC) product that's applied to the skin. Depending on the product, it could be safe to use in both children and adults. It comes as a patch, cream, lotion, ointment, and stick. Luckily methyl salicylate doesn't have many side effects, but it can sometimes cause a burning sensation after applying.

Indications for Methyl salicylate

Minor aches and pains in the muscles and joints caused by:

  • Arthritis
  • Backache
  • Strains
  • Sprains
  • Bruises
  • Damaged nerves

Pros and Cons for Methyl salicylate

Pros

  • Available OTC as a lower-cost generic
  • Can be applied directly to the painful area
  • Comes as a patch, cream, ointment, lotion, and stick
  • Generally well tolerated with few side effects

Cons

  • Can't be applied to irritated or damaged skin
  • Can't be used in people who are allergic to aspirin or salicylates
  • Possibly cause salicylate poisoning if using too much of the product
  • The patch won't stick well to damp skin

Common Side Effects for Methyl salicylate

  • Burning sensation

Warnings for Methyl salicylate

  • Salicylate poisoning
  • Risk of serious skin burns

Prices with our coupons for Lidoderm vs. Methyl salicylate

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Lidocaine30 patches / 5%
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Methyl Salicylate1 tube / 120g of 25%
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