Key takeaways
Latuda (lurasidone) and Zyprexa (olanzapine) are both atypical antipsychotics used to treat schizophrenia and bipolar disorder, but they have some key differences. Latuda is available only as an oral tablet, while Zyprexa comes in both oral and injectable forms. Latuda is less likely to cause weight gain compared to Zyprexa, which is known for its higher risk of weight gain and related issues like high blood sugar and cholesterol. Latuda is typically taken once daily with food, whereas Zyprexa can be taken with or without food. They are often taken in the evening due to their sleepiness side effects. Latuda is also associated with movement problems, while Zyprexa can cause anticholinergic side effects like dry mouth and constipation. Additionally, Zyprexa can be used in combination with fluoxetine (Prozac) for treatment-resistant depression, a use not indicated for Latuda.
