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Labetalol vs. Losartan

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Labetalol and losartan are both medications used to treat high blood pressure, but they belong to different drug classes. Labetalol, available only as a generic, is both an alpha blocker and a non-selective beta blocker, while losartan, also available as a generic, is an angiotensin II receptor blocker (ARB). Labetalol is typically taken twice a day and is often used during pregnancy, whereas losartan is usually taken once a day and is not safe for use during pregnancy. Labetalol can cause side effects like dizziness and tiredness, and it may lead to breathing problems in people with asthma. Losartan can cause dizziness and fatigue, and it may lead to high potassium levels, which can affect your kidneys. Both medications can interact with other blood pressure medications, increasing the risk of low blood pressure, while losartan can interact with medications like lithium and nonsteroidal anti-inflammatory drugs (NSAIDs). Both medications require a prescription, and you should talk to your healthcare team before making any changes to your treatment plan.

Labetalol

 

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Losartan

(Cozaar)

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Summary for Labetalol

Prescription only

Labetalol is a medication that works as both an alpha blocker and beta blocker. It's used to treat high blood pressure in adults. But it's not a first-choice medication for blood pressure, except during pregnancy. Labetalol is typically taken by mouth twice a day. It can also be given through the veins by a healthcare professional, usually in a hospital setting, to treat dangerously high blood pressure. Common side effects of oral labetalol include dizziness and feeling tired. This medication is only available as a generic; brand name Trandate has been discontinued.

Indications for Labetalol

Pros and Cons for Labetalol

Pros

Cons

  • Causes higher risk of wheezing and breathing problems compared to selective beta-blockers
  • Need to take twice a day (and three times a day for some people)
  • Stopping the medication suddenly can worsen chest pain

Common Side Effects for Labetalol

  • Dizziness (11%)
  • Nausea (6%)
  • Feeling tired (5%)
  • Indigestion (3%)
  • Stuffy nose (3%)
  • Headache (2%)

Warnings for Labetalol

  • Liver injury
  • Heart failure
  • Worsening chest pain and heart attacks
  • Risk of difficulty breathing
  • Hiding symptoms of low blood sugar
  • Greater risk during surgery
  • Risk of heart block (medication interaction)

Summary for Losartan

Prescription only

Losartan, also known by the brand name Cozaar, is a first-choice medication that's used to lower blood pressure. It's also shown to protect against stroke in certain people. In addition, this medication can slow down the worsening of kidney problems in certain people with diabetes. Losartan (Cozaar) belongs to the drug class called angiotensin II receptor blockers (ARBs). This medication is taken by mouth once daily and is available as a lower-cost generic. Side effects can include dizziness, fatigue, and upper respiratory infections.

Indications for Losartan

Pros and Cons for Losartan

Pros

Cons

Common Side Effects for Losartan

Warnings for Losartan

  • Harm to unborn baby
  • Low blood pressure
  • Kidney damage
  • High potassium levels

Prices with our coupons for Labetalol vs. Losartan

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Labetalol60 tablets / 100mg
$14.54$29.97
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Price Card Drug Icon
Losartan30 tablets / 50mg
$9.00$9.00
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