Key takeaways
Haldol (haloperidol) and Fanapt (iloperidone) are both used to treat schizophrenia, but they have some key differences. Haldol is a typical antipsychotic available as an injection and oral forms, while Fanapt is an atypical antipsychotic taken orally. Haldol works by blocking dopamine activity in the brain, which helps reduce hallucinations and delusions, whereas Fanapt stabilizes both dopamine and serotonin levels to improve mood, thoughts, and behaviors. Haldol is available as a lower-cost generic medication. Fanapt is also avaialble as a generic but it is only approved for schizophrenia. Haldol injections can be given as a monthly injection, while Fanapt needs to be taken twice a day. Possible side effects of both medications include movement-related issues, dizziness, dry mouth, and sleepiness. Both medications carry a risk of serious side effects, such as neuroleptic malignant syndrome and higher mortality in elderly people with dementia-related psychosis.
