Key takeaways
Glucovance (glyburide/metformin) and Lantus (insulin glargine) are both used to manage diabetes, but they have several differences between them. Glucovance is a combination of two medications, glyburide and metformin, taken to help manage blood sugar in adults with type 2 diabetes. Glyburide stimulates the pancreas to release insulin, while metformin reduces sugar production in the liver and improves insulin sensitivity. On the other hand, Lantus is a long-acting insulin injected under the skin, used for type 1 and type 2 diabetes. It helps your body absorb and store sugar from the bloodstream and stops the liver from making glucose. Glucovance must be taken with meals to avoid low blood sugar and stomach upset, while Lantus can cause weight gain and low blood sugar.
