Key takeaways
Dexmethylphenidate (Focalin, Focalin XR) and methylphenidate extended-release (Concerta, among other brands) are both stimulant medications used to treat ADHD, but they have some differences. Dexmethylphenidate is available in both immediate-release and extended-release forms, while methylphenidate ER comes in various formulations, including tablets, capsules, chewable tablets, and liquid. Dexmethylphenidate is typically taken twice a day for the immediate-release form and once a day for the extended-release form, whereas methylphenidate ER is usually taken once daily. Both medications can cause side effects like trouble sleeping and loss of appetite, stomach upset or pain, and irritabiltiy or nervousness. Methylphenidate ER has a broader range of available forms, which might offer more flexibility depending on your needs. Both medications carry risks of misuse and dependence and are controlled substances. However, methylphenidate ER is often considered a first-choice option for ADHD and is available in many lower-cost generic forms.
