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Focalin vs. Desoxyn

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dexmethylphenidate (Focalin, Focalin XR) and methamphetamine (Desoxyn) are both stimulant medications used to treat attention deficit-hyperactivity disorder (ADHD). However, they have some key differences. Dexmethylphenidate is more commonly prescribed and is available in both immediate-release and extended-release forms, while methamphetamine is rarely prescribed due to its higher risk of addiction and dependence. Dexmethylphenidate works by raising levels of norepinephrine and dopamine in the brain, whereas methamphetamine affects norepinephrine, serotonin, and dopamine. Methamphetamine is only available as a tablet, while dexmethylphenidate comes in both tablet and capsule forms. Both medications can cause serious side effects like heart problems and changes in behavior, but methamphetamine has additional risks such as seizures and is not safe for use during pregnancy.

Focalin

(dexmethylphenidate)

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Methamphetamine

(Desoxyn)

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Summary for Focalin

Prescription only

Dexmethylphenidate (Focalin, Focalin XR) is a stimulant medication that's used for treating attention deficit-hyperactivity disorder (ADHD) in adults and children. It's thought to work by balancing certain chemicals in your brain to help you focus. This medication is available as an immediate-release tablet that you take twice per day and an extended-release capsule you take once per day. Side effects can include stomach upset and nervousness. It can also cause withdrawal symptoms if it's suddenly stopped after long-term use. Focalin (dexmethylphenidate) is available as both a brand-name and lower-cost generic medication.

Indications for Focalin

  • Attention deficit-hyperactivity disorder (ADHD)

Pros and Cons for Focalin

Pros

  • Works well to treat ADHD in children and adults
  • Available as immediate-release tablets and extended-release capsules for a more flexible dosing schedule
  • Available as a lower-cost generic

Cons

  • A controlled substance because of the risk for misuse and dependency
  • Might cause trouble sleeping if you take too late in the day
  • Not the best option if you have heart problems
  • Not available as a liquid

Common Side Effects for Focalin

Immediate-release tablet Age 6 to 17 years:

  • Stomach pain (15%)
  • Nausea (9%)
  • Low appetite (6%)

Extended-release capsule Age 6 to 17 years:

  • Difficulty sleeping (up to 17%)
  • Vomiting (up to 9%)
  • Low appetite (up to 7%)

Age 17 to 60 years:

  • Headache (up to 39%)
  • Dry mouth (up to 20%)
  • Anxiety (up to 11%)
  • Indigestion (up to 9%)
  • Throat pain (up to 7%)

Warnings for Focalin

  • Misuse and dependence
  • Serious heart problems
  • Changes in behavior or thoughts
  • Prolonged and painful erection
  • Problems with blood circulation (Raynaud's phenomenon)
  • Slowed growth in children
  • Serotonin syndrome
  • Drug interactions

Summary for Desoxyn

Prescription only

Methamphetamine (Desoxyn) is a stimulant medication. It's FDA-approved to treat attention deficit-hyperactivity disorder (ADHD), but it's not commonly prescribed because other options are preferred. Some side effects of methamphetamine (Desoxyn) include restlessness, high blood pressure, and low appetite. Methamphetamine (Desoxyn) is a controlled substance with a risk of addiction and dependence.

Indications for Desoxyn

Pros and Cons for Desoxyn

Pros

  • Possible option for ADHD when other medications haven't worked
  • Taken by mouth
  • Available as a generic medication

Cons

  • Only available as a tablet
  • Might need to take twice daily
  • Not safe during pregnancy or breastfeeding

Common Side Effects for Desoxyn

  • High blood pressure
  • Fast heartbeat
  • Tremors
  • Trouble sleeping
  • Dizziness
  • Diarrhea or constipation
  • Low appetite
  • Dry mouth
  • Weight loss

Warnings for Desoxyn

  • Addiction, misuse, and dependence
  • Serious heart problems
  • Changes in behavior or thoughts
  • Seizures
  • Blood circulation problem (Raynaud's phenomenon)
  • Slowed growth in children
  • Serotonin syndrome
  • Worsening of motor and verbal tics

Prices with our coupons for Focalin vs. Desoxyn

Price Card Drug Icon
Dexmethylphenidate60 tablets / 10mg
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Price Card Drug Icon
Methamphetamine60 tablets / 5mg
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