Key takeaways
Farxiga (dapagliflozin) and Glyburide (Glynase) are both medications used to manage Type 2 diabetes. Both help lower your blood sugar (glucose), but they have several differences between them. Farxiga works by causing your kidneys to remove excess sugar through urine. It also has benefits for people with heart failure and chronic kidney disease (CKD). Glyburide, on the other hand, sends signals to your pancreas to release more insulin. Farxiga is typically taken once daily and is only available as a brand medication, while Glyburide can be taken once or twice daily and is available in both generic and brand forms. Farxiga has a lower risk of causing low blood sugar compared to Glyburide. Additionally, Farxiga isn't recommended during the second and third trimesters of pregnancy, whereas Glyburide's safety during pregnancy is not well-studied.
