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Compare Cogentin vs. Symmetrel

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Benztropine
    Amantadine
  • Benztropine
    Amantadine

  • Summary of Cogentin vs. Symmetrel

    Summary for Anticholinergic
    Prescription only

    Benztropine is an add-on medication used for the treatment of Parkinson's disease. It's also used for movement problems that are side effects from other medications, such as antipsychotics. It's no longer available as the brand name Cogentin, but still sold as the generic name benztropine. Dry mouth, trouble sweating, nausea, and fast heartbeat are some possible side effects of benztropine.

    Summary for NMDA antagonist
    Prescription only

    Amantadine is an NMDA antagonist. It's used to treat symptoms of movement disorders in adults, including Parkinson’s disease (PD). It works by raising the levels of dopamine in your body, which helps coordinate movements. Amantadine is taken by mouth, typically once or twice daily. Some side effects of this medication include nausea, dizziness, and trouble sleeping.

  • Indications of Cogentin vs. Symmetrel

    Indications for
    •Parkinson's disease (add-on medication)
    •Movement problems (extrapyramidal symptoms, or EPS) caused by antipsychotic medications
    Indications for
    •Parkinsonism, including Parkinson's disease (PD)
    •Extrapyramidal symptoms (uncontrolled body movements)

  • Pros and Cons of Cogentin vs. Symmetrel

    Pros and Const for Anticholinergic
    Pros
    •Dose can be easily adjusted based on your symptoms and side effects
    •Works together with other anti-parkinson medications
    •Available as a lower-cost generic medication
    Cons
    •Can cause severe dry mouth that can make it difficult to eat and speak
    •Not a good option for young children and older adults
    •Interacts with certain antipsychotics and tricyclic antidepressants (TCAs)
    Pros and Const for NMDA antagonist
    Pros
    •Taken by mouth
    •Might need to take only once daily
    •Available as a solution for people who've trouble swallowing pills
    Cons
    •Might not be a safe option during pregnancy
    •Not recommended to take with alcohol because can lead to dizziness and confusion
    •Can cause unusual urges or changes in mood

  • Common Side Effects of Cogentin vs. Symmetrel

    Common Side Effects for
    •Dry mouth
    •Nausea and vomiting
    •Constipation
    •Slowed gut movement
    •Fast heartbeat
    Common Side Effects for
    •Nausea (5-10%)
    •Dizziness (5-10%)
    •Trouble sleeping (5-10%)

  • Warnings of Cogentin vs. Symmetrel

    Common Side Effects for
    •Trouble thinking clearly
    •Slowed gut movement
    •Heat stroke
    •Muscle weakness
    •Mental health effects
    Common Side Effects for
    •Falling asleep during daily activities
    •Suicidal thoughts or behavior
    •Problems with mood and hallucinations
    •Low blood pressure and dizziness
    •High fever and confusion from withdrawal
    •Unusual urges and impulsive behaviors
    •Risk of death from overdose
    •Seizures
    •Heart failure
    •Kidney problems
    •Liver problems
    •Possible risk of skin cancer

  • Prices with our coupons for Cogentin vs. Symmetrel

    Learn more about Benztropine
    Learn more about Amantadine

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