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Compare Chlorpromazine vs. Thioridazine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Chlorpromazine
    Thioridazine
  • Chlorpromazine
    Thioridazine

  • Summary of Chlorpromazine vs. Thioridazine

    Summary for Typical antipsychotic
    Prescription only

    Chlorpromazine is an antipsychotic medication used to treat many conditions that affect the brain and nervous system, including schizophrenia, bipolar disorder, and ongoing hiccups. It works by blocking certain chemicals in the body, like histamine and dopamine. Your dose depends on why you’re taking it and how severe your symptoms are, but it’s usually taken three or four times a day. Common side effects include drowsiness and movement problems.

    Summary for First-generation (typical) antipsychotic
    Prescription only

    Thioridazine, previously known under the brand name Mellaril, treats adults and children with schizophrenia. This first-generation antipsychotic, or also called typical antipsychotic, is typically used only when other antipsychotic medications haven't worked well. Thioridazine tablets are taken by mouth a few times throughout the day. The dosage depends on how well the medication is helping with your symptoms and whether you're having side effects like dry mouth, sleepiness, and nausea. Thioridazine can also cause a serious heart rhythm problem called QT prolongation, so it's not a first-choice option.

  • Indications of Chlorpromazine vs. Thioridazine

    Indications for
    •Management of psychotic conditions
    •Schizophrenia
    •Nausea and vomiting
    •Restlessness and anxiety before surgery
    •Acute intermittent porphyria
    •Tetanus
    •Manic episodes of bipolar disorder
    •Hiccups that won't go away
    •Severe behavioral problems in children (ages 1 to 12) with extreme aggression or explosive behavior
    •Short-term treatment for children with hyperactivity, focus problems, or mood swings
    Indications for
    •Schizophrenia when other antipsychotic medications haven't worked well or have caused bothersome side effects

  • Pros and Cons of Chlorpromazine vs. Thioridazine

    Pros and Const for Typical antipsychotic
    Pros
    •Approved to treat several conditions
    •Starts working quickly
    •Available as a tablet, liquid, and injection
    •Dose can be easily adjusted based on your symptoms
    Cons
    •Needs to be taken multiple times a day
    •Commonly causes drowsiness
    •Risk of uncontrolled muscle movements
    •Not recommended for use in pregnancy
    Pros and Const for First-generation (typical) antipsychotic
    Pros
    •Less risk for weight gain than with atypical antipsychotics
    •Less likely to have problems with muscle movements than other antipsychotic medications
    •Available in many different strengths
    Cons
    •Must take many times a day
    •Not a first-choice option because it has many potential side effects
    •Can't take with certain medications, such as fluoxetine (Prozac) and propranolol (Inderal), because it raises the risk for dangerous changes in heart rhythm

  • Common Side Effects of Chlorpromazine vs. Thioridazine

    Common Side Effects for
    •Drowsiness
    •Dry mouth
    •Blurred vision
    •Constipation
    •Urination problems
    Common Side Effects for
    •Sleepiness
    •Dry mouth
    •Blurry vision
    •Constipation
    •Nausea
    •Vomiting
    •Diarrhea

  • Warnings of Chlorpromazine vs. Thioridazine

    Common Side Effects for
    •Higher risk of death in older adults with dementia
    •Uncontrolled muscle movements
    •Neuroleptic malignant syndrome
    •Changes in blood cell counts
    •High prolactin levels
    •Falls and fractures
    Common Side Effects for
    •Life-threatening abnormal heart rhythm (QT prolongation)
    •Higher risk of death in older people with dementia-related psychosis
    •Difficulty controlling body movements
    •Neuroleptic malignant syndrome (NMS)
    •Higher risk of falls
    •Lower white blood cell count (leading to possible risk for infection)
    •Possible high prolactin levels
    •Harm to an unborn baby

  • Prices with our coupons for Chlorpromazine vs. Thioridazine

    Learn more about Chlorpromazine
    Learn more about Thioridazine

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