Key takeaways
Citalopram (Celexa) and escitalopram (Lexapro) are both selective serotonin reuptake inhibitors (SSRIs) used to treat depression. However, there are some key differences between the two. Citalopram is only approved for treating depression, while escitalopram is approved for both depression and generalized anxiety disorder (GAD). Citalopram is typically taken once daily, and it may take a few weeks to a couple of months to feel its full effects. Escitalopram can also be taken once daily, but some people may notice improvements as early as one week after starting it. Both medications can cause side effects like nausea and trouble sleeping. But they tend to be better tolerated and have fewer drug interactions compared to other SSRIs. Additionally, escitalopram can be used in children aged 12 and older for depression, whereas citalopram is not FDA approved for children. Both medications carry risks of serious side effects like suicidal thoughts and serotonin syndrome, and they should not be stopped abruptly to avoid withdrawal symptoms.
