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Compare Zoloft vs. Celexa

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Sertraline (Zoloft) and citalopram (Celexa) are both selective serotonin reuptake inhibitors (SSRIs) used to treat mental health conditions, but they have some differences. Sertraline (Zoloft) is used for a wider range of conditions, including depression, OCD, panic disorder, PTSD, PMDD, and social anxiety disorder, while citalopram (Celexa) is primarily used for depression. Both medications are taken once daily and can cause side effects like nausea and sleep problems. However, sertraline (Zoloft) is available in both tablet and liquid forms, whereas citalopram (Celexa) comes in tablet, capsule, and mint-flavored liquid forms. Sertraline (Zoloft) is less likely to cause weight gain compared to some other SSRIs, while citalopram (Celexa) has a low risk for weight gain but can sometimes cause weight loss. Both medications can lead to withdrawal symptoms if stopped suddenly and have risks of serious side effects like serotonin syndrome and QT prolongation. Always consult your healthcare provider before making any changes to your medication.

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