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Viibryd vs. Celexa

Vilazodone (Viibryd) helps treat depression in adults. It works in a similar way to the drug class called selective serotonin reuptake inhibitors (SSRIs). You take vilazodone (Viibryd) by mouth once a day. Some common side effects are diarrhea, nausea, and headache. Research suggests that it might be less likely to cause weight gain and sexual side effects than some other antidepressants. But it can have many drug interactions. It's important not to stop taking this medication all of a sudden because it can lead to withdrawal symptoms. Vilazodone (Viibryd) comes as both a brand-name and generic version.

• Major depressive disorder (MDD) in adults

• Diarrhea (26-29%)
• Nausea (22-24%)
• Headache (14-15%)

• Suicidal thoughts or behavior
• Serotonin syndrome
• Higher risk of bleeding
• Manic or hypomanic episode in people with bipolar disorder
• Withdrawal symptoms
• Worsening of glaucoma in certain people
• Low sodium levels
• Sexual side effects

Citalopram (Celexa) is a first-choice medication for treating depression in adults. This antidepressant belongs to the drug class called selective serotonin reuptake inhibitors (SSRIs). Citalopram (Celexa) is typically taken by mouth once daily. It typically takes a few weeks or longer of consistent treatment to notice an improvement to your mood. Common side effects include nausea and dry mouth. There's a low risk for weight gain, but suddenly stopping the medication can lead to withdrawal symptoms (e.g., upset stomach, trouble sleeping, anxiety).

• Depression

• Nausea (21%)
• Dry mouth (20%)
• Sleepiness (18%)
• Trouble sleeping (15%)
• Sweating (11%)
• Tremor (8%)
• Diarrhea (8%)
• Ejaculation problems (6%)

• Worsening depression, suicidal thoughts, and unusual behavior
• Life-threatening abnormal heart rhythm (QT prolongation)
• Serotonin syndrome
• Withdrawal
• Higher risk of bleeding
• Not for use in bipolar disorder by itself
• Glaucoma
• Low sodium levels