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Betapace vs. Lopressor

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Sotalol (Betapace) and metoprolol tartrate (Lopressor) are both beta blockers, but they are used to treat different conditions. Sotalol is a non-selective beta blocker and potassium channel blocker, primarily used to treat and prevent certain heart rhythm problems like atrial fibrillation. It requires close monitoring in a hospital when you first start taking it. Metoprolol tartrate, on the other hand, is a selective beta blocker used to treat high blood pressure, chest pain, and to lower the risk of death after a heart attack. You typically take metoprolol tartrate with food, and it is less likely to cause breathing problems compared to sotalol. Both medications are available in generic forms, but sotalol also comes in an oral liquid form for those who have trouble swallowing tablets. While both can cause dizziness and tiredness, sotalol has a higher risk of causing serious heart rhythm issues and requires more frequent monitoring.

Sotalol

(Betapace)

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Metoprolol tartrate

(Lopressor)

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Summary for Betapace

Prescription only

Sotalol (Betapace) is used to treat and prevent certain types of heart rate and heart rhythm problems (like atrial fibrillation or Afib). It's taken by mouth, typically twice a day. Usually, you need to start this medication in the hospital and stay there for at least 3 days so that the healthcare team can monitor your heart rhythm and check for any serious side effects. Sotalol (Betapace) can interact with several medications, including certain blood pressure medications and antacids. Sotalol is available both generic and brand name medications.

Indications for Betapace

Pros and Cons for Betapace

Pros

  • Works well to treat life-threatening arrhythmias
  • Available in a lower-cost, generic version
  • Available as an oral liquid for people having trouble swallowing tablets

Cons

  • Must in a hospital for 3 days when first starting
  • Can cause serious arrhythmias, so it requires close monitoring
  • Can't use in people with certain medical conditions (e.g., heart failure, severe kidney problems, breathing problems)

Common Side Effects for Betapace

  • Tiredness (up to 20%)
  • Dizziness (up to 16%)
  • Low heart rate (up to 13%)
  • Headache (up to 12%)
  • Trouble breathing (up to 10%)

Warnings for Betapace

  • Life-threatening abnormal heart rhythm
  • Low blood pressure and heart rate
  • Heart failure
  • Difficulty breathing (bronchospasm)
  • Masked symptoms of low blood sugar
  • Heart issues with sudden discontinuation
  • Severe allergic reactions

Summary for Lopressor

Prescription only

Metoprolol tartrate (Lopressor) is a beta blocker used to treat chest pain and high blood pressure in adults. It can also lower the risk of death after a heart attack. You take it by mouth, typically once or twice a day, but your dose depends on your condition. Side effects include dizziness, shortness of breath, and it can make you tired.

Indications for Lopressor

Pros and Cons for Lopressor

Pros

  • Fast-acting — works quickly after you take it
  • First choice treatment after a heart attack
  • Available in different strengths, so your dose can be adjusted easily
  • Possible option for those who are breastfeeding

Cons

Common Side Effects for Lopressor

  • Tiredness (10%)
  • Dizziness (10%)
  • Diarrhea (5%)
  • Rash (5%)
  • Depression (5%)

Warnings for Lopressor

  • Risks of stopping treatment suddenly
  • Worsening heart failure
  • Risk of difficulty breathing
  • Major surgery
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of overactive thyroid
  • Severe allergic reactions

Prices with our coupons for Betapace vs. Lopressor

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Sotalol60 tablets / 80mg
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Metoprolol60 tablets / 25mg
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