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Aveed vs. Jatenzo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Aveed

(testosterone undecanoate)

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Jatenzo

(testosterone undecanoate)

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Summary for Aveed

Prescription only

Aveed (testosterone undecanoate) is an injectable testosterone that’s used to treat low testosterone in adult males. It's an FDA-approved testosterone replacement therapy that must be injected by a healthcare professional due to possible allergic reactions and a serious warning called pulmonary oil microembolism (POME), which causes symptoms such as coughing, chest pain, and trouble breathing. Initially, you'll receive the first two injections a month apart, then an injection every 10 weeks after that. Common side effects include acne, pain at the injection site, and fatigue.

Indications for Aveed

Pros and Cons for Aveed

Pros

  • Works well to replace testosterone in your body
  • Can be given every 10 weeks (after the first 2 injections)
  • No accidental testosterone exposure to another person through skin-to-skin contact like testosterone gels

Cons

  • Only available through a REMS program because of life-threatening side effects
  • Must be injected by your prescriber, so it can't be given at home
  • Only available as a brand-name medication

Common Side Effects for Aveed

  • Acne (5%)
  • Injection site pain (5%)
  • Rise in prostate-specific antigen (PSA, 5%)
  • Rise in estrogen levels (3%)
  • Tiredness (2%)
  • Irritability (2%)
  • Trouble sleeping (insomnia, 2%)
  • Mood swings (2%)

Warnings for Aveed

  • Pulmonary oil microembolism (POME) and severe allergic reactions
  • Prostate problems
  • Risk of blood clots, including heart attack or stroke
  • Potential for misuse, dependency, and addiction
  • Liver problems
  • Swelling in the legs or arms (edema)
  • Sleep apnea
  • High calcium in the blood

Summary for Jatenzo

Prescription only

Jatenzo (testosterone undecanoate) is an oral capsule used for testosterone replacement therapy (TRT) in adult males with hypogonadism, a condition that causes low testosterone production. You take a dose by mouth twice a day, once in the morning and once in the evening. Common side effects include headaches, high blood pressure, and nausea. This medication is only available as a brand-name medication, meaning there are no generic versions.

Indications for Jatenzo

Pros and Cons for Jatenzo

Pros

  • Works well to replace testosterone in the body
  • Comes as a capsule taken by mouth
  • Lower risk of liver problems compared to other testosterone products

Cons

  • Must take it twice a day
  • Can cause high blood pressure, which can raise your risk of serious heart problems
  • Requires regular blood tests to monitor testosterone and nutrient levels

Common Side Effects for Jatenzo

  • Headache (5%)
  • High red blood cell count (5%)
  • High blood pressure (4%)
  • Changes in cholesterol levels (3%)
  • Nausea (2%)

Warnings for Jatenzo

  • High blood pressure with risk of heart attack or stroke
  • High red blood cell count
  • Blood clots
  • Potential for misuse, dependency, and addiction
  • Worsening enlarged prostate and risk of prostate cancer
  • Liver problems
  • Lower sperm production
  • Swelling in the legs or arms (edema)
  • Breathing problems during sleep (sleep apnea)
  • High calcium in the blood
  • Depression and suicide thoughts

Prices with our coupons for Aveed vs. Jatenzo

Price Card Drug Icon
Aveed1 vial / 3ml of 750mg/3ml
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Jatenzo60 capsules / 237mg
$1,012.20$1,323.55
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