Jatenzo

Jatenzo (testosterone undecanoate) can raise your blood pressure, which increases the risk of serious heart problems, including heart attack and stroke. This is more likely to occur in people who already have heart problems or have risk factors for heart problems. Even a small blood pressure increase can raise this risk, even if you don’t notice any symptoms. Let your prescriber know and get emergency help right away if you experience symptoms of heart problems, such as:

Jatenzo (testosterone undecanoate) can increase your red blood cell count, which might lead to blood clots, heart attacks, and strokes. Your prescriber will check your red blood cell levels with blood tests every 3 months to make sure they stay in a healthy range. If your levels get too high, your prescriber might lower your dose or pause treatment until they return to normal. If your red blood cell levels rise again after restarting Jatenzo (testosterone undecanoate), you might need to stop the medication altogether to avoid serious blood clot risks.

Jatenzo (testosterone undecanoate) can cause life-threatening blood clots in your legs or lungs. Watch for symptoms of a blood clot in the legs, such as leg pain, swelling, or redness. Signs of a blood clot in the lungs include trouble breathing or chest pain. If you have any of these symptoms, tell your prescriber right away and get medical help right away, as you might need to stop the medication.

Jatenzo (testosterone undecanoate) is a controlled substance because it has a risk of misuse, dependency, and addiction, especially if taken at higher doses than prescribed or with other testosterones.

Taking Jatenzo (testosterone undecanoate) can worsen symptoms in people with an enlarged prostate, also known as benign prostatic hyperplasia (BPH). Let your prescriber know if you notice changes in urination, such as frequent nighttime urination, trouble urinating, a weak stream, urgency, or accidental leakage.

Using certain forms of testosterone, such as methyltestosterone and testosterone enanthate intramuscular injection, for a long time can cause serious liver problems. This isn't a known risk of Jatenzo (testosterone undecanoate), but it's still important to watch for signs of liver damage. Tell your prescriber if you have stomach pain, light-colored stools, dark urine, or if your skin or the whites of your eyes turn yellow, as you might need to stop the medication.

Taking high doses of testosterone, including Jatenzo (testosterone undecanoate), can lower sperm production by affecting hormone levels in the body. This might lead to reduced sperm count and other changes in semen quality. If you are planning to have children, talk to your prescriber about this possible risk before starting or continuing this medication.

Taking Jatenzo (testosterone undecanoate) can make your body hold onto extra salt and water, which might cause swelling in your legs or arms and sudden weight gain. This is more likely if you're also taking medications that cause swelling, like corticosteroids. It can be more serious in people with heart, liver, or kidney conditions. Swelling can be more serious if you have heart, liver, or kidney problems. If you notice swelling, talk to your prescriber, as you might need to stop Jatenzo (testosterone undecanoate) or take a diuretic (water pill) to help reduce fluid buildup.

Jatenzo (testosterone undecanoate) can worsen sleep apnea, a condition that causes breathing problems during sleep. This is more likely if you have risk factors like obesity or long-term lung disease. If you experience loud snoring, choking during sleep, or excessive daytime tiredness, talk to your prescriber.

If you have cancer and are at risk for high calcium levels (hypercalcemia), be careful when taking Jatenzo (testosterone undecanoate) or other androgens. Your prescriber might check your calcium levels regularly to make sure they stay in a safe range. If you notice symptoms like nausea, weakness, or confusion, contact your prescriber.