Tlando (testosterone undecanoate) is an oral capsule that's used to treat adult males with certain conditions that cause low or no testosterone. It comes in a convenient pill form that's taken by mouth twice a day. Common side effects of this medication include higher blood pressure and upper respiratory infections. While using Tlando (testosterone undecanoate), it's important to have regular blood tests to check your testosterone levels since your results will determine whether you should continue to use the medication.
Low testosterone levels from certain medical conditions
Testosterone is a hormone that your body makes. It's the main sex hormone in males and is responsible for development of male sex organs. Testosterone also plays a role in maintaining other body functions, such as muscle growth, sex drive, and sperm production.
Some males have low testosterone because of certain medical conditions or as a side effect of chemotherapy. Tlando (testosterone undecanoate) works by raising testosterone in the body to healthy levels.
Tlando (testosterone undecanoate) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: High blood pressure | Heart problems | High blood sugar | People identified as obese
Tlando (testosterone undecanoate) can raise your blood pressure. Higher blood pressure can lead to serious problems, such as heart attack, stroke, or sudden cardiac (heart-related) death. This is more likely to occur in people who already have heart problems or have risk factors for heart problems, such as high blood sugar. Your provider will check your blood pressure before you start Tlando (testosterone undecanoate), about 3 weeks after you begin treatment, and regularly after that. They'll also ask you to check your blood pressure at home. If you develop high blood pressure, your provider might ask you to start a blood pressure medication. If your blood pressure still remains high, you might need to stop taking Tlando (testosterone undecanoate).
Let your provider know and get emergency help right away if you experience symptoms of heart problems, such as:
Tlando (testosterone undecanoate) can cause a high red blood cell (RBC) count. This can raise your risk for blood clots, which can affect any part of your body, including the brain, heart, lung, and legs. Your provider will check your RBC levels about every 3 months during your first year of Tlando (testosterone undecanoate) treatment, and then every 6 months after that. Get emergency help right away if you have symptoms of stroke, heart attack, or of blood clots in other parts of the body, including:
Risk factors: Taking more Tlando (testosterone undecanoate) than prescribed | Taking Tlando (testosterone undecanoate) with other testosterones
Tlando (testosterone undecanoate) is a controlled substance because of its potential for misuse. People have misused Tlando (testosterone undecanoate) by taking it for reasons other than what's prescribed. Misusing Tlando (testosterone undecanoate) can cause serious heart and mental health problems, such as heart attack, heart failure, stroke, liver problems, depression, delusions, hallucinations, and aggression.
Misusing Tlando (testosterone undecanoate) can also lead to addiction and dependence. Some symptoms of addiction include taking higher doses of Tlando (testosterone undecanoate) than prescribed and continuing to take this medication despite experiencing serious health problems related to the medication. Dependence can lead to withdrawal symptoms, such as depression, tiredness, and irritability.
Only take Tlando (testosterone undecanoate) as prescribed by your provider.
Risk factors: History of enlarged prostate
Taking Tlando (testosterone undecanoate) can worsen certain symptoms in people with an enlarged prostate, or benign prostatic hyperplasia (BPH). Let your provider know if you experience any changes in your urinary routine, such as more urination at night, feeling like you need to urinate more often or immediately, trouble urinating, accidentally urinating, or urinating slowly.
Tlando (testosterone undecanoate) can also raise your risk of prostate cancer. Your provider might have you perform occasional blood tests and physical check-ups before and during treatment. Tlando (testosterone undecanoate) isn't recommended if you have prostate cancer, because it might worsen your cancer.
Using injectable testosterone, such as methyltestosterone and testosterone enanthate intramuscular injection, for long periods of time can cause life-threatening liver problems. This isn't a known risk of Tlando (testosterone undecanoate), but it's important to look out for signs and symptoms of liver damage. Let your provider know if you're experiencing stomach pain, light-colored stools, dark urine, or if your skin or the whites of your eyes turn yellow, because you might need to stop the medication.
Risk factors: History of heart, liver, or kidney conditions | Taking other medications that cause swelling like corticosteroids
Taking Tlando (testosterone undecanoate) can cause your body to hold onto more salt and water, which can lead to swelling in your legs or arms and sudden weight gain. This is more likely to happen if you're also taking other medications that cause swelling, such as corticosteroids (e.g., prednisone, methylprednisolone (Medrol)). It can be more serious in people with heart, liver, or kidney conditions. Talk to your provider if you have any of these symptoms, because you might need to stop Tlando (testosterone undecanoate) or take other medications (e.g., water pills or diuretics) to help with this problem.
Risk factors: History of sleep apnea | History of obesity | History of lung disease
Tlando (testosterone undecanoate) can worsen symptoms in people who have breathing problems while they sleep. This is more likely to happen to people who also have a history of obesity or lung conditions. If you experience more daytime sleepiness or if your partner notices that you stop breathing in your sleep more often, talk to your provider.
Risk factors: History of cancer | Taking other medications that cause high calcium in the blood
Tlando (testosterone undecanoate) can raise calcium levels in the blood, especially in people with cancer. Too much calcium can lead to muscle weakness and kidney problems, such as frequent urination, thirst, stomach pain, and blood in the urine. During treatment with Tlando (testosterone undecanoate), your provider might have you perform regular blood tests to make sure your calcium levels are within the normal range.
Tlando (testosterone undecanoate) can raise prolactin levels in your blood. Prolactin is a hormone that's responsible for making breast milk during and after pregnancy. Normally, males have low levels of prolactin. But taking Tlando (testosterone undecanoate) can cause that level to become higher than normal. This can lead to larger breasts, discharge from the nipples, sexual problems, and lower amounts of body hair. Your provider will check your prolactin level before you start Tlando (testosterone undecanoate) and again 3 to 4 months into your treatment. If your prolactin levels are too high, your provider might tell you to stop taking the medication.
Source: DailyMed
Works well to replace testosterone in your body
Capsules are taken by mouth twice a day
Only one single recommended dose, so the dose stays the same even if your testosterone levels change
Must be taken with food
Can cause high blood pressure, which can raise your risk of serious heart conditions
Can interact with common medications (e.g., insulin, oral blood thinners, and corticosteroids)
Take Tlando (testosterone undecanoate) twice daily, in the morning and the evening, with food. Taking Tlando (testosterone undecanoate) with food helps it absorb into your system better, which will give you a better response from the medication.
Take Tlando (testosterone undecanoate) exactly as prescribed by your provider. This medication is only FDA-approved for the treatment of low testosterone in males with certain medical conditions. Taking Tlando (testosterone undecanoate) in any other way can cause serious side effects, such as heart attack, heart failure, stroke, depression, hallucinations, and delusions.
Tlando (testosterone undecanoate) can often cause the breast area in males to become bigger, painful, or tender. This might continue throughout treatment. Let your provider know if this becomes bothersome.
Tlando (testosterone undecanoate) can raise your blood pressure, so it's important to check your blood pressure occasionally while taking this medication. If your blood pressure can't be controlled while taking Tlando (testosterone undecanoate), your provider might tell you to stop taking it.
Tlando (testosterone undecanoate) can cause high blood pressure, which can raise your risk of heart attacks and strokes. Many medications used to treat other conditions can also raise your blood pressure. Before starting any new medications, it's important to check with your provider or pharmacist about any interactions.
Tlando (testosterone undecanoate) can lower your blood sugar. You might need to monitor your blood sugar more often while taking this medication, especially if you take insulin. Make sure you know how to recognize and treat low blood sugar. Talk to your provider if you have diabetes and are experiencing any symptoms of low blood sugar, including shakiness, sweating, fast heartbeat, and confusion, because you might require changes to your medications.
Taking Tlando (testosterone undecanoate) might raise the level of fats in your blood. Your provider will order blood work from time to time to check if the level of fats are in a safe range. If your levels are high, your provider might prescribe you a medication to bring down the level of fats or recommend that you stop taking Tlando (testosterone undecanoate).
Taking Tlando (testosterone undecanoate) together with blood thinners, like warfarin (Coumadin), can cause you to bleed more easily. Your provider might monitor your blood clotting time more often when you're taking this medication. Let your provider know if you experience bleeding that takes longer to stop, bruising, blood in your urine, or dark stools, as the dose of your blood thinner might need to be adjusted.
Tlando (testosterone undecanoate) can lower the amount of sperm you make, which can make it more difficult for you to have a baby. This is more likely to happen when using higher doses of Tlando (testosterone undecanoate). This side effect can become permanent, so talk to your provider before starting Tlando (testosterone undecanoate) if you're trying to have a baby.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
112.5mg | 120 capsules | $728.23 | $6.07 |
The typical dose is 225 mg (2 capsules) by mouth twice a day, once in the morning and once in the evening.
Males with breast cancer or prostate cancer
Females who are pregnant
Males with low testosterone without certain medical conditions, such as having low testosterone due to age
Low testosterone levels from certain medical conditions
Low testosterone (hypogonadism)
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Antares Pharma, Inc. (2023). Tlando- testosterone undecanoate capsule, liquid filled [package insert]. DailyMed.
MedlinePlus. (2020). Prolactin levels.
You and Your Hormones. (2020). Testosterone.
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