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Atarax vs. Klonopin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Hydroxyzine (Vistaril) and clonazepam (Klonopin) are both used to treat anxiety, but they belong to different medication classes and have distinct uses and side effects. Hydroxyzine is an antihistamine that can also help with itching and allergies, while clonazepam is a benzodiazepine primarily used for seizures and panic disorder. Hydroxyzine is not a controlled substance and is available in both pill and liquid forms, whereas clonazepam is a Schedule IV controlled substance due to its potential for misuse and dependence. Clonazepam is typically taken two to three times a day and can cause side effects like drowsiness, dizziness, and poor movement control. Hydroxyzine can also cause drowsiness and dry mouth, but it is generally not recommended for long-term use due to a lack of studies on its long-term safety and effectiveness. Additionally, clonazepam should not be stopped abruptly to avoid withdrawal symptoms, while hydroxyzine does not have this issue. Both medications should be used with caution in certain populations, such as older adults and those with specific health conditions.

Hydroxyzine HCl

(Atarax)

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Clonazepam

(Klonopin)

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Summary for Atarax

Prescription only

Hydroxyzine hydrochloride (Atarax) is a prescription antihistamine for adults and children. It's used to treat anxiety and to ease itching from allergies. It's also used as a sleep aid (sedative) before and after general anesthesia. Hydroxyzine HCl (Atarax) comes as tablet and oral solution that are taken by mouth up to 4 times per day. Common side effects include sleepiness and dry mouth.

Indications for Atarax

Pros and Cons for Atarax

Pros

  • Starts to work within 30 minutes
  • Available as a tablet and a liquid that are taken by mouth
  • Can use in children

Cons

Common Side Effects for Atarax

Warnings for Atarax

  • Sleepiness
  • Heart rhythm problems (QT prolongation)
  • Higher risk of side effects in people over 65
  • Severe allergic and skin reactions

Summary for Klonopin

Prescription only

Clonazepam (Klonopin) is a benzodiazepine. It's approved to treat seizures in adults and children, and panic disorder in adults only. Clonazepam (Klonopin) is taken by mouth, typically two or three times a day. It's also available as orally disintegrating tablets (ODTs) for people who have trouble swallowing. Some common side effects of this medication include drowsiness, dizziness, and poor movement control. Before stopping clonazepam (Klonopin), speak with your prescriber to come up with a plan to lower your dose slowly over time to avoid withdrawal symptoms.

Indications for Klonopin

Pros and Cons for Klonopin

Pros

Cons

  • Taken 2 to 3 times daily
  • Can be habit-forming, so isn't typically used for long-term treatment
  • Can cause memory problems, drowsiness, dizziness, and confusion
  • Might not work as well for seizure control over time

Common Side Effects for Klonopin

Seizures:

  • Drowsiness (50%)
  • Poor movement control, clumsiness (30%)
  • Behavior problems (25%)

Panic Disorder:

  • Drowsiness (up to 50%)
  • Dizziness (up to 12%)
  • Runny nose, sore throat, and other symptoms of a respiratory infection (up to 10%)
  • Extreme tiredness (up to 9%)
  • Poor movement control, clumsiness (up to 9%)
  • Depression (up to 8%)

Warnings for Klonopin

  • Sedation and difficulty breathing
  • Potential for misuse, addiction, dependence, and withdrawal
  • Suicidal thoughts or behaviors
  • Effect on driving and concentration
  • Harm to babies
  • Worsening of seizures

Prices with our coupons for Atarax vs. Klonopin

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Hydroxyzine Hydrochloride30 tablets / 25mg
$8.34$18.58
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Clonazepam30 tablets / 0.5mg
$9.72$34.50
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