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Anoro Ellipta vs. Breo Ellipta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Anoro Ellipta (umeclidinium/vilanterol) and Breo Ellipta (fluticasone/vilanterol) are both inhalers used to manage chronic obstructive pulmonary disease (COPD), but they have some key differences. Anoro Ellipta combines a long-acting muscarinic antagonist (LAMA) and a long-acting beta-agonist (LABA), while Breo Ellipta combines an inhaled corticosteroid (ICS) and a LABA. This means Anoro Ellipta focuses on relaxing airway muscles and opening airways, whereas Breo Ellipta also reduces inflammation in the lungs. Anoro Ellipta is only used for COPD, but Breo Ellipta can also be used for asthma. Breo Ellipta has a generic version available, making it potentially more affordable than Anoro Ellipta, which does not have a generic form. Additionally, you need to rinse your mouth after using Breo Ellipta to prevent fungal infections, a step not required with Anoro Ellipta. Both inhalers are taken once daily and are not suitable for sudden breathing problems.

Anoro Ellipta

(umeclidinium / vilanterol)

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Breo Ellipta

(fluticasone furoate / vilanterol)

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Summary for Anoro Ellipta

Prescription only

Anoro Ellipta is a steroid-free inhaler that contains umeclidinium (a long-acting muscarinic antagonist, or LAMA) and vilanterol (a long-acting beta agonist, or LABA). It's FDA-approved for maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. This Ellipta inhaler is inhaled through the mouth once per day. Side effects aren't common, but some people have reported sore throat and diarrhea.

Indications for Anoro Ellipta

Pros and Cons for Anoro Ellipta

Pros

  • Combination of two bronchodilators within a single inhaler
  • Inhaled once per day
  • No need to rinse your mouth after a dose since it doesn't contain a steroid

Cons

  • Doesn't replace your rescue inhaler for sudden trouble breathing
  • Can't use if you're severely allergic to milk proteins because it contains lactose
  • Might not be a good choice for people who've trouble urinating

Common Side Effects for Anoro Ellipta

  • Sore throat (2%)
  • Diarrhea (2%)

Warnings for Anoro Ellipta

  • Not for COPD flare ups or worsening breathing
  • Narrowing of your airways (bronchospasm)
  • Serious allergic reactions
  • Worsening narrow-angle glaucoma
  • Trouble urinating
  • Heart problems
  • Low potassium level in the blood

Summary for Breo Ellipta

Prescription only

Breo Ellipta (fluticasone furoate / vilanterol) is a maintenance inhaler used every day to help manage asthma and chronic obstructive pulmonary disease (COPD). It's a combination of two medications: fluticasone, a corticosteroid that reduces swelling in your lungs, and vilanterol, a long-acting beta agonist (LABA) that helps relax your airways. The typical dose is one puff by mouth once a day. Breo Ellipta (fluticasone furoate / vilanterol) isn't for sudden breathing problems or asthma attacks. Side effects include oral thrush, sore throat, and headache.

Indications for Breo Ellipta

Pros and Cons for Breo Ellipta

Pros

  • Long-term treatment for both COPD and asthma
  • Inhaled only once a day
  • Might be easier to use compared to some other dry powder inhalers
  • Safe for children 5 years and older for asthma

Cons

  • Won't work well for asthma attacks or COPD flare ups
  • Not safe for those severely allergic to milk proteins since it contains lactose
  • Can cause thrush in mouth or throat
  • No need to prime or shake the inhaler before use

Common Side Effects for Breo Ellipta

Asthma (adults):

  • Common cold symptoms (7-10%)
  • Headache (5-8%)

Asthma (children):

  • Common cold symptoms (10%)
  • Upper respiratory tract infection (7%)

COPD:

  • Common cold symptoms (9%)
  • Upper respiratory tract infection (7%)
  • Headache (7%)
  • Oral thrush (5%)

Warnings for Breo Ellipta

  • Worsening asthma or COPD
  • Overdose
  • Oral thrush
  • Pneumonia
  • Higher risk of infection
  • Changes in stress hormone levels
  • Sudden narrowing of the airways
  • Serious allergic reactions
  • Heart problems
  • Risk of bone loss
  • Slowed growth in children
  • Eye problems
  • High blood sugar and low potassium

Prices with our coupons for Anoro Ellipta vs. Breo Ellipta

Price Card Drug Icon
Umeclidinium/Vilanterol Ellipta1 inhaler / 60 blisters of 62.5mcg/25mcg
$273.88$552.93
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Price Card Drug Icon
Fluticasone Furoate/Vilanterol Ellipta1 inhaler / 60 blisters of 100mcg/25mcg
$228.01$415.96
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