Timolol gel is a beta blocker that's used to lower pressure within the eye and treat glaucoma. It's a gel-forming eye drop that can be used by itself or together with other eye drops that aren't beta blockers. The brand name, Timoptic-XE, was discontinued, but the generic version is still available. The usual dosage is a drop of timolol gel in the eye(s) once a day. A common side effect is blurry vision, but it often doesn't last longer than 5 minutes after using the medication.
High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)
Timolol gel is a beta blocker that lowers the amount of fluid in the eye. When there's less fluid inside the eye, the eye pressure goes down.
This particular timolol product becomes a gel when it makes contact with your eye, and it gets washed away by your tears.
Source:Â DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Chest pain or discomfort
lightheadedness, dizziness, or fainting
shortness of breath
slow or irregular heartbeat
unusual tiredness
Rare
Noisy breathing
small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope
swelling of hands, ankles, feet, or lower legs
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Blurred vision
continuing ringing or buzzing or other unexplained noise in ears
headache
hearing loss
nervousness
pounding in the ears
sweating
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Rare
Acid or sour stomach
belching
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
decreased interest in sexual intercourse
feeling of constant movement of self or surroundings
inability to have or keep an erection
indigestion
lack or loss of strength
loss in sexual ability, desire, drive, or performance
sensation of spinning
stomach discomfort, upset, or pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Works well to treat high eye pressure
Only used once daily
Can use in people as young as 2 years of age
Lower-cost generic version available
Common to have blurry vision as a side effect
Shouldn't use if you have asthma or other lung problems
Risk of similar side effects as timolol tablets since some medication can absorb into your bloodstream
Hasn't been studied in people who wear contact lenses
Wash your hands before each time you use timolol gel. Don't let the bottle tip touch your eye or any other surface, and avoid touching the tip with your hands. This prevents the medication from getting contaminated with germs and is helpful for avoiding eye infections.
Remove your contact lenses before applying timolol gel. Wait 15 minutes after you use the medication to put your lenses back in. This medication wasn't studied for use in people who wear contact lenses, but it contains a preservative that might cause damage to your lenses.
Before each time you use timolol gel, turn the bottle upside down and shake it once.
If you need to use other eye drop medications in addition to timolol gel, wait 10 minutes after you use them before you place timolol gel into your eye(s).
It's not easy to tell whether your eye pressure is improving at home. Make sure to use timolol gel as prescribed, even if you don't notice any difference in your symptoms or vision right away.
Don't try to make the hole on the tip of the timolol gel bottle larger. The tip makes sure one drop comes out at a time, and making a larger hole can cause you to use too much medication.
Timolol gel can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Congestive heart failure | Second- or third-degree heart block
In rare cases, some people developed heart failure while they used beta-blocking medications like timolol gel. People who already have heart failure might be at risk for worsening heart problems with this medication. Tell your healthcare team about your medical history. And talk to your primary care provider if you notice swelling in your feet or ankles, a fast or irregular pulse, or shortness of breath when you lie down or exercise. These might be signs of heart problems.
Risk factors: History of asthma | History of chronic obstructive pulmonary disease (COPD) | History of other lung problems
Beta blocker medications like timolol gel usually aren't recommended for people with lung problems, like asthma and COPD. This is because beta blockers can cause the airways to become narrower, which can make it harder to breathe. But the risk for breathing problems specifically with timolol gel isn't well known. So make sure your healthcare team knows if you have or have ever had any lung problems or conditions before you start using this medication to check whether it's safe for you.
Risk factors: Diabetes
Beta blockers can cause people with diabetes to not notice symptoms of low blood sugar, except for sweating and dizziness. It's possible for some timolol gel to be absorbed into your bloodstream and cause this effect. So though rare, it's important to be aware of this risk. Talk to your primary care provider to see whether you should check your blood sugar more often if you're using timolol gel.
Beta blockers can cause people with an overactive thyroid to not recognize the signs of hyperthyroidism, such as a fast heart rate. It's possible for some timolol gel to be absorbed into your bloodstream and cause this effect. Although rare, it's good to be aware of this risk. Make sure your primary care provider knows that you're using timolol gel so they can monitor your thyroid problem more closely.
In some rare cases, timolol gel can worsen symptoms like muscle weakness in people who have myasthenia gravis. Watch out for worsening symptoms if you have myasthenia gravis and let the specialist who's monitoring your condition know if this happens to you.
The typical dose is 1 drop in the affected eye(s) once daily.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Asthma
Sinus bradycardia (slow heart rate)
Second- or third-degree heart block
High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)
High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)
High pressure in the eye caused by ocular hypertension (high blood pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)
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