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Compare Neptazane vs. Azopt

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Methazolamide and brinzolamide (Azopt) are both carbonic anhydrase inhibitors used to lower eye pressure and treat conditions like glaucoma. Methazolamide, available as a generic, is taken orally in tablet form, typically 2 or 3 times a day. In contrast, brinzolamide is an eye drop applied directly to the eye, usually 3 times daily. While methazolamide is FDA-approved for lowering eye pressure, brinzolamide is specifically approved for ocular hypertension and open-angle glaucoma. Methazolamide can cause side effects like tingling in the arms or legs, ringing in the ears, and stomach upset. Brinzolamide can cause blurry vision and a bitter taste, and it should be avoided if you have a sulfa allergy. Methazolamide is generally more affordable as a generic, while brinzolamide, despite having a generic version, tends to be more expensive.

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