Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Dorzolamide (Trusopt) and timolol (Betimol) are both eye drop medications used to lower eye pressure and treat glaucoma, but they belong to different drug classes and work differently. Dorzolamide is a carbonic anhydrase inhibitor that reduces the amount of fluid in the eye, while timolol is a beta blocker that also lowers fluid production. Dorzolamide is typically used three times a day, whereas timolol is usually taken once or twice daily. Dorzolamide can cause side effects like eye irritation and a bitter taste, and it is not safe for people with sulfa allergies. On the other hand, timolol can cause burning or stinging in the eye and is not recommended for people with asthma, COPD, or certain heart conditions. Both medications are available in generic forms, making them more affordable.
Dorzolamide
Timolol
Dorzolamide
Timolol
Summary of Trusopt vs. Timolol
Summary for Carbonic anhydrase inhibitor
Prescription only
Dorzolamide is an eye drop medication used to treat high pressure in the eye in people with glaucoma or ocular hypertension. The dosage is 1 drop applied directly into the affected eye(s) three times per day. It's available as a generic only as the brand-name medication Trusopt has been discontinued. Dorzolamide is a sulfa medication, so it might not be the best choice if you have a serious sulfa allergy. Side effects include burning or stinging in the eye and a bitter taste in the mouth.
Summary for Beta blocker
Prescription only
Timolol is an eye drop medication that's used to lower pressure within the eye and treat glaucoma. This medication belongs to the drug class called beta blockers. Timolol can be used by itself or together with other eye drops. The usual dosage is a drop of timolol into the eye(s) once or twice a day. Common side effects include burning or stinging after you put in the eye drops, but this is generally a temporary feeling. Although the brand name Timoptic was discontinued, the generic version is still available.
Indications of Trusopt vs. Timolol
Indications for
Treatment of high pressure in the eye in people with: