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Compare Nayzilam vs. Keppra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nayzilam (midazolam) and Keppra (levetiracetam) are both used to treat seizures, but they have some key differences. Nayzilam (midazolam) is a benzodiazepine nasal spray used for quick relief during seizure attacks in people 12 years and older. It works by slowing down brain activity and is only available as a brand-name medication. On the other hand, Keppra (levetiracetam) is an antiepileptic medication available in both brand and generic forms. It comes in various oral formulations, including immediate-release and extended-release tablets, and is used for long-term seizure control. Keppra (levetiracetam) is taken daily and can be used by children as young as one month old. While Nayzilam (midazolam) is used as needed for seizure attacks, Keppra (levetiracetam) is taken regularly to prevent seizures. Additionally, Nayzilam (midazolam) requires special training to know when and how to use it properly, whereas Keppra (levetiracetam) does not have these instructions for use but can cause mood changes and behavioral issues, especially in children.

  • Nayzilam (midazolam)
    Levetiracetam (Keppra)
  • Nayzilam (midazolam)
    Levetiracetam (Keppra)

  • Summary of Nayzilam vs. Keppra

    Summary for Benzodiazepine
    Prescription only

    Nayzilam (midazolam) is a nasal spray that quickly treats seizure attacks in people with a seizure condition called epilepsy. It comes in a ready-to-use spray device, but the person giving the medication must know when and how to give it properly. Nayzilam (midazolam) commonly causes drowsiness, throat irritation, and nasal discomfort. Nayzilam (midazolam) is only available as a brand-name medication.

    Summary for Antiepileptic
    Prescription only

    Immediate-release levetiracetam is a seizure medication for adults and children. It's known as the brand names Keppra and Roweepra, and it also has a generic version. This medication comes as a tablet and liquid that's taken twice each day. The dosage depends on your age, weight, and the type of seizure you have. Levetiracetam (Keppra) doesn't have any known interactions with food or medications. Common side effects include weakness, sleepiness, and headache.

  • Indications of Nayzilam vs. Keppra

    Indications for
    •Seizure attacks in people with epilepsy who are 12 years of age and older
    Indications for
    •Focal aware (partial-onset) seizures in people ages 1 month and older
    •Add-on treatment for myoclonic seizures from juvenile myoclonic epilepsy in people ages 12 years and older
    •Add-on treatment for generalized tonic-clonic seizures in people ages 6 years and older

  • Pros and Cons of Nayzilam vs. Keppra

    Pros and Const for Benzodiazepine
    Pros
    •Works within 10 minutes to treat seizure attacks
    •Might help prevent another seizure attack from happening within 24 hours
    •Good option for someone who can't take anything by mouth, such as in the middle of a seizure attack
    Cons
    •Only for treating seizure attacks, not for long-term seizure control
    •Caregivers need special training to know when and how to give the medication properly.
    •Can't use in children younger than 12 years of age
    •Only available as a brand-name medication
    Pros and Const for Antiepileptic
    Pros
    •Available as tablets and a liquid (liquid recommended for children weighing 44 lbs or less)
    •Taken by mouth with or without food
    •Usually tolerated well
    Cons
    •Need to take twice per day
    •Might cause changes in behavior or mood
    •Might not be the best option if you have a history of mental health problems (e.g., depression, schizophrenia, bipolar disorder)

  • Common Side Effects of Nayzilam vs. Keppra

    Common Side Effects for
    •Drowsiness (10%)
    •Nasal discomfort (9%)
    •Headache (4%)
    •Throat irritation (3%)
    •Runny nose (3%)
    Common Side Effects for

    Side effects were reported by people with focal aware seizures taking levetiracetam (Keppra) with other seizure medications. Side effects might differ for other seizure types. <br> Adults:

    •Weakness (15%)
    •Sleepiness (15%)
    •Headache (14%)
    •Infection (13%)
    •Dizziness (9%)

    Children:

    •Headache (19%)
    •Common cold symptoms (15%)
    •Vomiting (15%)
    •Sleepiness (13%)
    •Tiredness (11%)
    •Being aggressive (10%)
    •Cough (9%)
    •Stuffy nose (9%)
    •Upper stomach pain (9%)
    •Lower appetite (8%)

  • Warnings of Nayzilam vs. Keppra

    Common Side Effects for
    •Extreme sleepiness and difficulty breathing
    •Misuse and addiction
    •Dependence and withdrawal
    •Suicidal thoughts or behaviors
    •Difficulty with concentration, focus, and memory
    •Rise in eye pressure in people with glaucoma
    Common Side Effects for
    •Abnormal mood, thoughts, or behavior
    •Suicidal thoughts or behavior
    •Difficulty with speech, movement, and concentration
    •Serious allergic reactions and skin reactions
    •Withdrawal seizures
    •Low blood cell counts
    •Higher blood pressure in young children
    •Seizure control during pregnancy

  • Prices with our coupons for Nayzilam vs. Keppra

    Learn more about Nayzilam
    Learn more about Levetiracetam

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