Key takeaways
Valtoco (diazepam) and Nayzilam (midazolam) are both benzodiazepines used to treat seizure attacks in people with epilepsy, but they have some key differences. Valtoco is approved for use in children as young as 6 years old, while Nayzilam is only for those 12 and older. Valtoco comes in multiple doses (5 mg, 10 mg, 15 mg, and 20 mg), whereas Nayzilam is available in a single 5 mg dose. Valtoco can be used up to twice in a 24-hour period, and Nayzilam allows for a second dose if the seizure isn't controlled after 10 minutes. Both medications are nasal sprays and work quickly, but Valtoco typically works within 4 minutes, while Nayzilam can take up to 10 minutes. Additionally, Valtoco and Nayzilam are only available as a brand-name medication. Common side effects for both include drowsiness, headache, and nasal discomfort.
