Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Dorzolamide and Lumigan (bimatoprost) are both eye drop medications used to treat high pressure in the eye, such as in conditions like ocular hypertension and open-angle glaucoma. However, they belong to different medication classes. Dorzolamide is a carbonic anhydrase inhibitor, while Lumigan is a prostaglandin. Dorzolamide is typically used three times a day, whereas Lumigan is used once daily in the evening. Dorzolamide is available as a lower-cost generic, while Lumigan's 0.01% strength is only available as a brand-name product. Common side effects of dorzolamide include burning or stinging in the eye and a bitter taste in the mouth, while Lumigan can cause eye redness, eyelash growth, and eye itching. Dorzolamide may not be suitable for those with a sulfa allergy, and Lumigan can cause permanent darkening of the eye color. Both medications require careful handling to avoid contamination and potential eye infections.
Dorzolamide
Lumigan (bimatoprost)
Dorzolamide
Lumigan (bimatoprost)
Summary of Trusopt vs. Lumigan
Summary for Carbonic anhydrase inhibitor
Prescription only
Dorzolamide is an eye drop medication used to treat high pressure in the eye in people with glaucoma or ocular hypertension. The dosage is 1 drop applied directly into the affected eye(s) three times per day. It's available as a generic only as the brand-name medication Trusopt has been discontinued. Dorzolamide is a sulfa medication, so it might not be the best choice if you have a serious sulfa allergy. Side effects include burning or stinging in the eye and a bitter taste in the mouth.
Summary for Prostaglandin
Prescription only
Lumigan (bimatoprost) is an eye drop that's used to treat conditions related to high pressure in the eye, including glaucoma. It belongs to the drug class called prostaglandins, which work in the eye to reduce eye pressure. The brand name Lumigan is the 0.01% strength of the eye drops. There's also a 0.03% strength of generic bimatoprost eye drops for glaucoma. People 16 years of age or older can use either strength. This eye drop is used once a day in the evening. Side effects include eye redness, itchy eyes, and eye irritation.
Indications of Trusopt vs. Lumigan
Indications for
Treatment of high pressure in the eye in people with: