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Compare Trusopt vs. Xalatan

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dorzolamide and latanoprost (Xalatan and Xelpros) are both medications used to treat high pressure in the eye caused by conditions like ocular hypertension and open-angle glaucoma. However, they belong to different medication classes. Dorzolamide is a carbonic anhydrase inhibitor, while latanoprost is a prostaglandin. Dorzolamide is typically used as an eye drop three times a day, whereas latanoprost is used once daily in the evening. Dorzolamide is available only as a generic, while latanoprost is available in both brand and generic forms. Common side effects of dorzolamide include burning or stinging in the eye and a bitter taste, while latanoprost can cause changes in eye color and eyelash growth. Dorzolamide can be combined with other medications like brimonidine, whereas latanoprost should not be used more than once daily as it can become less effective. Both medications require careful handling to avoid contamination and potential eye infections.

  • Dorzolamide
    Latanoprost (Xalatan)
  • Dorzolamide
    Latanoprost (Xalatan)

  • Summary of Trusopt vs. Xalatan

    Summary for Carbonic anhydrase inhibitor
    Prescription only

    Dorzolamide is an eye drop medication used to treat high pressure in the eye in people with glaucoma or ocular hypertension. The dosage is 1 drop applied directly into the affected eye(s) three times per day. It's available as a generic only as the brand-name medication Trusopt has been discontinued. Dorzolamide is a sulfa medication, so it might not be the best choice if you have a serious sulfa allergy. Side effects include burning or stinging in the eye and a bitter taste in the mouth.

    Summary for Prostaglandin
    Prescription only

    Latanoprost (Xalatan) helps lower pressure in the eye and is a popular medication for glaucoma, but it can cause changes to your eyelashes and eye color.

  • Indications of Trusopt vs. Xalatan

    Indications for

    Treatment of high pressure in the eye in people with:

    •Ocular hypertension
    •Open-angle glaucoma
    Indications for
    •High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)

  • Pros and Cons of Trusopt vs. Xalatan

    Pros and Const for Carbonic anhydrase inhibitor
    Pros
    •Doesn't typically cause side effects throughout the rest of your body
    •Can be combined with other medications
    •Safe to use in children
    Cons
    •Needs to be used 3 times a day
    •Can cause eye irritation right after applying a drop
    •Not the best option if you're allergic to sulfa medications
    Pros and Const for Prostaglandin
    Pros
    •Good at treating high eye pressure
    •Only used once a day
    •Causes less eye irritation than many alternatives
    •Xalatan brand is available as a cheaper, generic form.
    Cons
    •Can permanently change the color of your eyes
    •Can trigger herpes infections of the eye
    •Requires removal of soft contact lenses
    •Xelpros brand has no generic available

  • Common Side Effects of Trusopt vs. Xalatan

    Common Side Effects for
    •Burning or stinging in the eye (33%)
    •Bitter taste (25%)
    •Bacterial eye infection (10-15%)
    •Allergic reaction in the eye (10%)
    Common Side Effects for
    •Temporary stinging right after using (55% with Xelpros, 9% with Xalatan)
    •Red eye (41% with Xelpros, not common with Xalatan)
    •Red eyelids (15% with Xelpros, 8% with Xalatan)
    •Feeling like there is something in your eye (13% with Xalatan, 2% with Xelpros)
    •Eye discharge, extra "sleepers" in your eyes (12% with Xelpros, not common with Xalatan)
    •Eyelash growth (11% with Xelpros, not common with Xalatan)
    •Eye inflammation (10% with Xalatan, 1% with Xelpros)
    •Blurry vision (8% with Xalatan, not common with Xelpros)
    •Itchy eyes (8% with Xalatan, 5% with Xelpros)
    •Eye burning (7% with Xalatan, not common with Xelpros)
    •Darker eye color (7% with Xalatan, not common with Xelpros)

  • Warnings of Trusopt vs. Xalatan

    Common Side Effects for
    •Severe allergic reactions
    •Risk for eye infection (from contamination)
    •Risk for swelling of the cornea
    Common Side Effects for
    •DARKER EYES, EYELIDS, OR EYELASHES
    •MORE EYELASHES
    •EYE INFLAMMATION AND SWELLING
    •HERPES INFECTIONS
    •BACTERIAL INFECTIONS
    •NO SOFT CONTACT LENSES

  • Prices with our coupons for Trusopt vs. Xalatan

    Learn more about Dorzolamide
    Learn more about Latanoprost

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