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Lumigan vs. Vyzulta

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Lumigan

(bimatoprost)

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Vyzulta

(latanoprostene bunod)

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Summary for Lumigan

Prescription only

Lumigan (bimatoprost) is an eye drop that's used to treat conditions related to high pressure in the eye, including glaucoma. It belongs to the drug class called prostaglandins, which work in the eye to reduce eye pressure. The brand name Lumigan is the 0.01% strength of the eye drops. There's also a 0.03% strength of generic bimatoprost eye drops for glaucoma. People 16 years of age or older can use either strength. This eye drop is used once a day in the evening. Side effects include eye redness, itchy eyes, and eye irritation.

Indications for Lumigan

Pros and Cons for Lumigan

Pros

  • Only used once a day
  • Starts to work within 4 hours and lasts for at least 8 to 12 hours
  • One of the first-choice options for open-angle glaucoma

Cons

  • Might permanently darken the color of your eyes
  • Need to take out any soft contact lenses before using
  • Hasn't been studied for children younger than 16 years of age

Common Side Effects for Lumigan

  • Eye redness (up to 45%)
  • Eyelash growth (up to 45%)
  • Itchy eye (up to 45%)

Warnings for Lumigan

  • Darker eyes or eyelids
  • Eyelash changes
  • Eye inflammation
  • Swelling of the retina (macular edema)
  • Risk of bacterial eye infection when using contaminated medication
  • Don't use while wearing soft contact lenses

Summary for Vyzulta

Prescription only

Latanoprostene bunod ophthalmic solution, also known by its brand name Vyzulta, is the only prostaglandin that also releases nitric oxide along with latanoprost acid, working in two ways to help lower eye pressure. This eye drop medication is used to treat conditions related to high pressure in the eye, such as glaucoma. Vyzulta (latanoprostene bunod) is approved for people 17 years of age and older. It's given as a drop into the affected eye(s) once daily in the evening. Bottles should be refrigerated, but they can be stored at room temperature for up to 8 weeks after opening. Side effects include eye redness and eye pain.

Indications for Vyzulta

Pros and Cons for Vyzulta

Pros

Cons

  • Can change the color of your eyes
  • No lower-cost generic available; brand-name medication only
  • Not recommended for children age 16 and younger because of possible permanent changes to eye color with long-term use

Common Side Effects for Vyzulta

  • Red eyes (6%)
  • Eye irritation (4%)
  • Eye pain (3%)
  • Eye pain after placing the drop into the eye (2%)

Warnings for Vyzulta

  • Darker eyes, eyelashes, or eyelids
  • Eyelash changes
  • Eye inflammation
  • Swelling of the retina (macular edema)
  • Risk for bacterial infection in the eye when using contaminated medication
  • Don't use while wearing soft contact lenses

Prices with our coupons for Lumigan vs. Vyzulta

Price Card Drug Icon
Bimatoprost1 eye dropper / 2.5ml of 0.01%
$77.98$289.31
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Price Card Drug Icon
Vyzulta1 eye dropper / 2.5ml of 0.024%
$266.73$331.94
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