Skip to main content
Granisetron Coupon - Granisetron 1mg tablet

granisetron

Generic Kytril
Used for Nausea

Granisetron prevents nausea and vomiting due to chemotherapy and radiation. It can cause headaches and can be more expensive than other similar medications like ondansetron (Zofran).

Reviewed by:
reviewerHope Chang, PharmD, AAHIVP
reviewerMichelle Nguyen, PharmD
Last reviewed on August 17, 2021
basics-icon

What is Granisetron?

What is Granisetron used for?

  • Prevention of nausea and vomiting associated with cancer medications (chemotherapy) and radiation

How Granisetron works

Granisetron is an antiemetic. It works by blocking the actions of serotonin in the body that can trigger nausea and vomiting.

Drug facts

Common BrandsKytril(brand no longer available)
Drug ClassAntiemetic
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
side-effects-icon

Side effects of Granisetron

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (20%)
  • Weakness or lack of energy (18%)
  • Constipation (14%)
  • Diarrhea (9%)
  • Upset stomach and stomach pain (4—6%)

Less Common Side Effects

  • Dizziness
  • Trouble sleeping (insomnia)
  • Anxiety

Granisetron serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serotonin syndrome: Confusion, fever, fast heart rate, sweating, muscle stiffness or spasms

Source: DailyMed

The following Granisetron side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Severe constipation

Incidence not known

Anxiety

arm, back, or jaw pain

black, tarry stools

bleeding gums

blood in the urine or stools

blurred vision

chest pain or discomfort

chest tightness or heaviness

chills

confusion

cough

diarrhea

difficulty with swallowing

dizziness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fainting

fast, slow, or irregular heartbeat

fever

headache

hives or welts, itching, or skin rash

muscle spasms or twitching

nausea

nervousness

painful or difficult urination

pain, itching, redness, irritation, blistering, burning, discoloration, or rash where the patch is applied

pale skin

pinpoint red spots on the skin

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redness of the skin

restlessness

seeing, hearing, or feeling things that are not there

sleepiness or unusual drowsiness

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stomach pain or swelling

sweating

swollen glands

trouble breathing

unusual bleeding or bruising

unusual tiredness or weakness

vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Decreased appetite

hair loss or thinning of the hair

lack or loss of strength

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

prices-container

Get your GoodRx coupon

Avg retail price
$Infinity(Save 100.00%)
GoodRx discount
$13.77
See prices
pros-and-cons-icon

Pros and cons of Granisetron

Pros

  • Can be taken orally or by injection
  • Safe option for older adults and people with kidney and liver problems
  • Only needs to be taken on chemotherapy and radiation days

Cons

  • Only prevents nausea and vomiting; not as good of an option for treatment of nausea and vomiting that is already present
  • Tablets not for use in children
  • Can be more expensive than similar medications
pharmacist-tips-icon

Pharmacist tips for Granisetron

pharmacist
  • Take granisetron tablets 1 hour before receiving chemotherapy or radiation on the day of treatment. If you're taking two separate doses, take the first dose 1 hour before chemotherapy and the second dose 12 hours later.
  • You will usually have to take multiple medications that work together to prevent nausea and vomiting from cancer treatment. Make sure you take your antiemetics correctly and ask your provider if you have questions about your regimen.
  • Let your provider know if you have a history of heart problems, or if you take medications that can affect the way your heart beats. Sometimes, granisetron can lead to heart-related problems when taken with certain other medications.
  • Let your healthcare team know if you've ever had an allergic reaction to an antiemetic before. They might want to monitor you closely for a reaction.
faq-icon

Common questions about Granisetron

Granisetron and ondansetron (Zofran) both work on serotonin receptors to prevent nausea and vomiting. They are used for different conditions and have different prices. Sometimes, one might work better than the other for certain people. Both medications come in many different forms; see below for a side-by-side comparison.

The brand-name product Kytril has been discontinued, but the generic product is available. It's not clear why the manufacturer (Roche) decided to stop making the brand medication, but the FDA reports that it wasn't for safety reasons.

It's not known if granisetron can harm your unborn baby. Talk to your provider if you're pregnant or have plans on becoming pregnant.

Granisetron can be taken with or without food. It's important to remember that this medication is taken about an hour before chemotherapy or radiation. Talk to your care team about good dietary options on treatment days.

educational-icon

How to save using GoodRx

Compare Prices
1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
Select your free coupon
2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
Show coupon to your pharmacist
3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
Get free couponLearn more
warnings-icon

Risks and warnings for Granisetron

Granisetron can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Serotonin syndrome

  • Risk factors: Taking other medications that can affect the serotonin levels in your brain

Serotonin syndrome is a rare, but potentially life-threatening condition where there's too much serotonin active in the brain. Your risk goes up if you use granisetron with other medications that affect serotonin levels, such as antidepressants (e.g., escitalopram (Lexapro)), lithium, tramadol (Ultram), sumatriptan (Imitrex), and St. John's Wort. Symptoms of too much serotonin include a fast heart rate, sweating, muscle stiffness or spasms, fever, and confusion. Tell your provider right away if you have any of these symptoms.

Heart rhythm problems

  • Risk factors: History of heart rhythm | Taking other medications causing heart rhythm problems

People taking antiemetics like granisetron can have changes with their heart rhythm. It's more likely to happen in people with a history of heart problems or take other medications that can affect their heartbeat. Make sure your healthcare team knows your medical history and a full list of your medications.

Digestion problems

  • Risk factors: Stomach surgery | Taking opioid medications

There have been reports of severe constipation in people taking granisetron. It can also mask symptoms of intestinal (gut) blockage or bloating. Pay attention to how often you're having bowel movements, and contact your provider if you have constipation, problems passing gas, and pain or swelling in your stomach area.

dosage-icon

Granisetron dosage

The average cost for 30 tablets of 1mg of Granisetron is $44.40 with a free GoodRx coupon. This is 73.78% off the average retail price of $169.34.
tabletTablet
DosageQuantityPrice as low asPrice per unit
1mg30 tablets$44.40$1.48
vialVial
DosageQuantityPrice as low asPrice per unit
1ml of 0.1mg/ml1 vial$13.77$13.77
1ml of 1mg/ml2 vials$15.47$7.74
4ml of 1mg/ml1 vial$33.30$33.30

Typical dosage for Granisetron

  • Chemotherapy-associated nausea and vomiting: The typical dose is 2 mg by mouth per day on the days you receive chemotherapy. It can either be taken as 2 mg once daily or 1 mg twice daily.
  • Radiation-associated nausea and vomiting: The typical dose is 2 mg by mouth within 1 hour of radiation.

Granisetron is also available as an intravenous (IV) infusion that is administered by a healthcare provider.

interactions-icon

Interactions between Granisetron and other drugs

Granisetron may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Granisetron. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

cost-icon

How much does Granisetron cost?

To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
Granisetron (generic)
GoodRx lowest price

$13.77

(save 91.87%)
View prices and coupons
alternatives-icon

What are alternatives to Granisetron?

There are a number of medications that your doctor can prescribe in place of Granisetron. Compare a few possible alternatives below.
Granisetron
Used for:
  • Prevention of nausea and vomiting associated with cancer medications (chemotherapy) and radiation
$13.77Lowest GoodRx priceView prices
Used for:
  • Prevention of nausea and vomiting due to cancer medications (chemotherapy) or radiation therapy
  • Prevention of nausea and vomiting after surgery
$6.03Lowest GoodRx priceView prices
Used for:
  • Prevention of nausea and vomiting caused by chemotherapy
View prices
images-icon

Granisetron images

White Triangle G1 - Granisetron Hydrochloride 1mg Tablet
This medicine is White, Triangle Tablet Imprinted With "G1".White Triangle G1 - Granisetron Hydrochloride 1mg Tablet

Get savings updates for Granisetron

Receive price alerts, news, and other messages from GoodRx about Granisetron and other healthcare topics and relevant savings offers.

By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men's health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

Compare other Nausea drugs

Granisetron vs EmendGranisetron vs ReglanGranisetron vs SancusoGranisetron vs ZyprexaZofran vs GranisetronAbilify vs ZyprexaCompazine vs ReglanEmend vs ReglanGeodon vs ZyprexaHaldol vs ZyprexaLamictal vs ZyprexaLatuda vs ZyprexaLoxapine vs ZyprexaNeurontin vs ZyprexaPhenergan vs SancusoRisperdal vs ZyprexaSancuso vs EmendSancuso vs ReglanSancuso vs ZyprexaScopolamine vs SancusoSeroquel vs ZyprexaSustol vs ReglanSustol vs ZyprexaThiothixene vs ZyprexaTrifluoperazine vs ZyprexaVraylar vs ZyprexaZofran vs ReglanZofran vs SancusoZyprexa vs AristadaZyprexa vs Reglan