Medications for Parkinson's disease are used to manage symptoms of Parkinson's, such as tremors and restlessness. They work by either affecting certain chemicals in the brain. Common classes include dopamine replacement medications, dopamine agonists, anticholinergics, and N-methyl-D-aspartate (NMDA) antagonists. Dopamine replacement medications include carbidopa / levodopa (Sinemet) and are taken orally.. Dopamine agonists like pramipexole (Mirapex ER) and ropinirole are usually taken as oral pills. Anticholinergics, such as benztropine (Cogentin), can be taken orally or as an injection. NMDA antagonists like amantadine (Gocovri) come in oral forms. These medications come in various forms, including extended-release options, to help manage your symptoms effectively.