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Zebeta vs. Bystolic

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Bisoprolol (bisoprolol fumarate) and nebivolol (Bystolic) are both beta blockers used to treat high blood pressure, but they have some differences. Bisoprolol is a cardioselective beta blocker, meaning it mainly targets the heart and is less likely to cause breathing problems compared to non-selective beta blockers. Nebivolol, on the other hand, not only slows down the heart rate but also relaxes blood vessels, which helps lower blood pressure further. While both medications are taken once daily, bisoprolol is available only as a generic, whereas nebivolol is available as both a brand name (Bystolic) and a generic. Nebivolol is less likely to cause erectile dysfunction and weight gain compared to other beta blockers, including bisoprolol. Both medications can cause dizziness and tiredness, and you should avoid alcohol while taking them to prevent worsening these side effects. Additionally, neither medication should be stopped suddenly without consulting your healthcare provider, as this can lead to serious heart problems.

Bisoprolol

 

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Nebivolol

(Bystolic)

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Summary for Zebeta

Prescription only

Bisoprolol, or bisoprolol fumarate, is a tablet that's used to treat high blood pressure. It belongs to a group of medications called beta blockers. It's usually only given when first-choice blood pressure medications aren't working well enough. Some common side effects of bisoprolol include headache, feeling tired, and diarrhea. It has some interactions with alcohol and taking bisoprolol with alcohol can worsen dizziness and raise the risk for fainting.

Indications for Zebeta

  • High blood pressure

Pros and Cons for Zebeta

Pros

  • Works well to lower blood pressure
  • Available as a lower-cost generic
  • Only need to take it once a day
  • Can take it with or without food

Cons

  • Not a first-choice medication to lower blood pressure
  • Skipping or missing doses can lead to high blood pressure and higher risk of heart attacks
  • Can make you feel more tired
  • Can hide symptoms of low blood sugar if you have diabetes

Common Side Effects for Zebeta

  • Headache (9%)
  • Fatigue (7%)
  • Upper respiratory tract infection (5%)
  • Swelling in arms or legs (4%)
  • Dizziness (3%)
  • Runny nose (3%)

Warnings for Zebeta

  • Heart attack or irregular heart rhythm
  • Heart failure
  • Trouble breathing (people with bronchospastic conditions)
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of high thyroid hormone
  • Severe allergic reactions
  • Worsening of poor circulation

Summary for Bystolic

Prescription only

Nebivolol (Bystolic) is a beta blocker. It's used to treat high blood pressure in adults, but it's not a first-choice medication for this condition. The typical dose is to take one tablet by mouth daily. Some of the more common side effects of nebivolol (Bystolic) include dizziness and tiredness. Don't drink alcohol while taking this medication because doing so can worsen dizziness. Nebivolol (Bystolic) is less likely to cause erectile dysfunction and weight gain compared to other beta blockers. It's available as both brand name Bystolic and generic nebivolol.

Indications for Bystolic

Pros and Cons for Bystolic

Pros

  • Only need to take it once a day
  • Can be taken with or without food
  • Less likely to cause certain side effects, like erectile dysfunction, compared to other beta blockers
  • Available as a lower-cost generic

Cons

  • Not a first-choice medication to lower blood pressure
  • Can hide symptoms of low blood sugar if you have diabetes
  • Not recommended if you're breastfeeding
  • Can't suddenly stop the medication because it can raise your risk of chest pain or heart attack

Common Side Effects for Bystolic

  • Headache (6-9%)
  • Tiredness (2-5%)
  • Dizziness (2-4%)
  • Diarrhea (2-3%)
  • Nausea (1-3%)

Warnings for Bystolic

  • Heart attack or irregular heart rhythm
  • Risk of difficulty breathing
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of high thyroid hormone
  • Risk during surgery
  • Severe allergic reactions

Prices with our coupons for Zebeta vs. Bystolic

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Bisoprolol30 tablets / 5mg
$9.00$9.00
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Nebivolol30 tablets / 5mg
$11.97$153.36
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