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Nebivolol Coupon - Nebivolol 10mg tablet

nebivolol

Generic Bystolic
Used for Hypertension
Used for Hypertension

Nebivolol (Bystolic) is a beta blocker. It's used to treat high blood pressure in adults, but it's not a first-choice medication for this condition. The typical dose is to take one tablet by mouth daily. Some of the more common side effects of nebivolol (Bystolic) include dizziness and tiredness. Don't drink alcohol while taking this medication because doing so can worsen dizziness. Nebivolol (Bystolic) is less likely to cause erectile dysfunction and weight gain compared to other beta blockers. It's available as both brand name Bystolic and generic nebivolol.

Reviewed by:
reviewer
Allison Gourley, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on June 13, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsLatest newsImagesReferencesPricesMedicare
basics-icon

What is Nebivolol (Bystolic)?

What is Nebivolol (Bystolic) used for?

How Nebivolol (Bystolic) works

Nebivolol (Bystolic) is a beta blocker. It mainly works by blocking certain receptors on the heart, which slows down heart rate and lowers blood pressure. Nebivolol (Bystolic) is unique from other beta blockers since it also relaxes blood vessels to further lower blood pressure.

When does Nebivolol (Bystolic) start working?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Full effect

Drug Facts

Common BrandsBystolic
Drug ClassBeta blocker
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Nebivolol (Bystolic)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (6-9%)
  • Tiredness (2-5%)
  • Dizziness (2-4%)
  • Diarrhea (2-3%)
  • Nausea (1-3%)

Other Side Effects

  • Chest pain
  • Stomach pain
  • Swelling in arms or legs
  • Trouble sleeping
  • Shortness of breath
  • Rash
  • Tingling sensation

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Bronchospasm: tightness in the chest, trouble catching your breath, difficulty breathing, wheezing, cough, dizziness, extreme tiredness
When do Nebivolol (Bystolic) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Dizziness
Tiredness

Source: DailyMed

More on Nebivolol (Bystolic) side effects

bystolic: side effects bystolic

7 Bystolic Side Effects: Headache, Nausea, and More

Written by Brian Leonard, PharmD, BCACP, BCGP

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Bloating or swelling of the face, arms, hands, lower legs, or feet

chest pain or discomfort

difficult or labored breathing

lightheadedness, dizziness, or fainting

rapid weight gain

shortness of breath

slow or irregular heartbeat

tightness in the chest

tingling of the hands or feet

unusual tiredness or weakness

unusual weight gain or loss

wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Absence of or decrease in body movement

anxiety

blue lips, fingernails, or skin

blurred vision

chills

cold sweats

coma

confusion

cool, pale skin

cough

decreased urine output

depression

dilated neck veins

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

dry mouth

extreme fatigue

fast heartbeat

headache

increased hunger

increased sweating

increased thirst

irregular, fast or slow, or shallow breathing

loss of appetite

mood changes

muscle pain or cramps

nausea or vomiting

nervousness

nightmares

noisy breathing

numbness in the hands, feet, or lips

seizures

shakiness

slurred speech

troubled breathing

vomiting

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Mild headache

Less common

Diarrhea

rash

sleeplessness

trouble sleeping

unable to sleep

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Nebivolol (Bystolic)

thumbs-up

Pros

Only need to take it once a day

Can be taken with or without food

Less likely to cause certain side effects, like erectile dysfunction, compared to other beta blockers

Available as a lower-cost generic

thumbs-down

Cons

Not a first-choice medication to lower blood pressure

Can hide symptoms of low blood sugar if you have diabetes

Not recommended if you're breastfeeding

Can't suddenly stop the medication because it can raise your risk of chest pain or heart attack

pharmacist-tips

Pharmacist tips for Nebivolol (Bystolic)

pharmacist

  • Nebivolol (Bystolic) can be taken with or without food. And it works best to lower your blood pressure if you take it regularly and continuously.

    • Don't suddenly stop taking nebivolol (Bystolic) without talking to your healthcare professional (HCP) because it can lead to chest pain and even a heart attack. If you need to stop this medication for some reason, your HCP will work with you to lower your dose slowly over time before stopping it completely.

      • If you accidentally forgot to take your dose of nebivolol (Bystolic), take it as soon as you remember, unless it's close to the time you normally take your next dose. But if it's too close, skip the dose and continue to take the next scheduled dose. Never double your dose to make up for a missed dose. Doing so can lead to dangerously low blood pressure. If you have questions about how to take nebivolol (Bystolic), contact your prescriber.

        • Nebivolol (Bystolic) can make you feel more tired or dizzy, especially in the first few days or when your dose is raised. If you feel dizzy, sit or lie down and tell your HCP right away. For your safety, make sure you know how this medication affects you before driving or performing activities that require you to be alert.

          • Some medications can raise the levels of nebivolol (Bystolic), which can lead to severely low blood pressure. Make sure to tell your healthcare team about all of the medications you're taking so they can adjust your dose of nebivolol (Bystolic) if needed.

            • Accidentally taking too much nebivolol (Bystolic) can lead to dangerously low blood pressure, dizziness, vomiting, and low blood sugar. If you or a loved one has taken too much nebivolol (Bystolic), get medical help right away or call a Poison Center at 1-800-222-1222.

              faqs

              Frequently asked questions about Nebivolol (Bystolic)

              Does nebivolol (Bystolic) cause weight gain?
              People who take nebivolol (Bystolic) typically don't report weight gain as a side effect. There are other beta blockers that are more likely to cause weight gain. To lower your risk of weight gain while taking nebivolol (Bystolic), it's important to eat a nutritious diet and try to do 30 minutes of moderate-intensity exercise for 5 days a week. Tell your healthcare team if you notice a sudden change in your weight while taking this medication so they can help figure out the cause and let you know if you need more medical attention.
              Can I take nebivolol (Bystolic) twice a day?
              Typically, nebivolol (Bystolic) is taken just once a day. One dose will work to control your blood pressure throughout the entire day. It doesn't matter if you take your dose in the morning or the evening, but it's important to be consistent with when you take it each day.
              Does nebivolol (Bystolic) cause hair loss?
              People who took nebivolol (Bystolic) in clinical studies didn't report hair loss (alopecia) as a side effect. If you experience hair loss while taking this medication, speak with your healthcare professional (HCP) and they can help determine the cause.
              What medications should you avoid when you're taking nebivolol (Bystolic)?
              Ask your healthcare team to help you check for medication interactions before you start nebivolol (Bystolic). There are certain medications that can interact with nebivolol (Bystolic). Most of the time, you don't need to avoid taking them with nebivolol (Bystolic), but your care team might adjust the doses of certain medications and monitor you more closely for side effects. Examples of these include some antidepressants, like fluoxetine (Prozac) and paroxetine (Paxil). There are a few medications you might need to avoid completely while taking nebivolol (Bystolic), and these include other beta blockers and clonidine.
              Can you cut nebivolol (Bystolic) in half?
              You can tell if your nebivolol (Bystolic) can be split in half if it's scored, meaning if it has a line down the middle showing where it should be split. If so, you're recommended to use a pill cutter to help you split the tablet evenly. If your nebivolol (Bystolic) doesn't have a score line, ask your healthcare team if it's possible for you to cut the medication in half.
              Can you drink alcohol while you're taking nebivolol (Bystolic)?
              It's best to avoid drinking alcohol while you're taking nebivolol (Bystolic). Drinking alcohol regularly can raise your blood pressure, and this will make it harder for nebivolol (Bystolic) to work to control your blood pressure. Additionally, drinking alcohol can worsen certain side effects, like dizziness, lightheadedness, and fainting.
              How well does nebivolol (Bystolic) work to lower blood pressure?
              In one study that lasted over 9 months, people who only took nebivolol (Bystolic) for blood pressure saw a drop in their systolic and diastolic blood pressures by about 15 mmHg each. In a separate study looking at people who were already taking other blood pressure medications, adding nebivolol (Bystolic) dropped their systolic blood pressure by about 4 mmHg to 6 mmHg, and diastolic blood pressure by about 3 mmHg to 5mmHg. Your healthcare team can talk with you about what you might expect after starting nebivolol (Bystolic).
              How quickly does nebivolol (Bystolic) work?
              You might notice your blood pressure going down within 2 weeks of starting nebivolol (Bystolic). Typically, your healthcare team will have you start at a lower dose to minimize the risk of side effects, like dizziness and tiredness. And if needed, they'll raise your dose every couple of weeks until your blood pressure is within a goal range. You might need to stay at a certain dose of nebivolol (Bystolic) for 2 to 8 weeks to experience the maximum benefit. Remember, not everyone responds to medications the same way. When you first start nebivolol (Bystolic), it's best to check your blood pressure regularly and share your numbers with your healthcare team at your appointments so they know how to best adjust your dose.
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              warings-icon

              What are the risks and warnings for Nebivolol (Bystolic)?

              Nebivolol (Bystolic) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Heart attack or irregular heart rhythm

              • Risk factors: Stopping nebivolol (Bystolic) suddenly

                Never stop taking nebivolol (Bystolic) suddenly without talking to your prescriber, especially if you have heart disease. Doing so can cause irregular heart rhythm, high blood pressure, and poor blood circulation to your heart. It can also raise your risk of chest pain or heart attack. If you need to stop taking nebivolol (Bystolic), work with your prescriber to lower your dose gradually over time, typically over 1 to 2 weeks.

                risk-warning

                Risk of difficulty breathing

                • Risk factors: Chronic obstructive pulmonary disease (COPD) | Asthma

                  Beta-blocker medications like nebivolol (Bystolic) are generally not recommended for people with bronchospastic conditions, like asthma, because it can trigger difficulty breathing. Nebivolol (Bystolic) has a lower risk of triggering this side effect because it tends to target the heart and not the lungs. But nebivolol (Bystolic) should only be taken under careful supervision of a healthcare professional (HCP) if you have any conditions that can cause breathing problems.

                  risk-warning

                  Hiding symptoms of low blood sugar

                  • Risk factors: Diabetes

                    Taking nebivolol (Bystolic) can make it difficult for you to identify symptoms of low blood sugar, such as fast heart beat or tremors. If you’re taking medications, like glipizide or insulin, to lower your blood sugar, you might not be able to rely on all the typical symptoms of low blood sugar (e.g., irritability, sight tremors, confusion, and fast heartbeat) to warn you of a dangerous drop in your sugar levels. Sweating might be the only symptom not affected by taking nebivolol (Bystolic). Speak with your healthcare provider about when and how to monitor your blood sugar if you start nebivolol (Bystolic).

                    risk-warning

                    Hiding symptoms of high thyroid hormone

                    • Risk factors: Hyperthyroidism

                      Nebivolol (Bystolic) can hide signs of hyperthyroidism, especially a fast heart rate. It's important to talk to your HCP before stopping nebivolol (Bystolic) suddenly, since doing so can worsen thyroid problems.

                      risk-warning

                      Risk during surgery

                      • Risk factors: Major surgery requiring anesthesia

                        Both beta-blockers and medications used for anesthesia can lower your heart rate. So, if you’re planning to undergo a major surgery that requires anesthesia, tell your surgeon that you’re on nebivolol (Bystolic) so that they can monitor your heart closely.

                        risk-warning

                        Severe allergic reactions

                        • Risk factors: History of severe allergic reaction

                          Beta blockers like nebivolol (Bystolic) can lessen your response to life-saving treatments of severe allergic reactions (anaphylaxis). They can also cause your allergic reaction to be more severe than usual. Discuss all of your allergies with your HCP and a plan on what to do if you experience an allergic reaction while taking nebivolol (Bystolic).

                          dosage

                          Nebivolol (Bystolic) dosage forms

                          The average cost for 30 tablets of 10mg of Nebivolol (Bystolic) is $10.80 with a free GoodRx coupon. This is 91.05% off the average retail price of $120.64.
                          tablet
                          Tablet
                          DosageQuantityPrice as low asPrice per unit
                          2.5mg90 tablets$14.40$0.16
                          5mg90 tablets$15.30$0.17
                          10mg30 tablets$10.80$0.36
                          20mg90 tablets$19.80$0.22

                          Typical dosing for Nebivolol (Bystolic)

                          The typical starting dose is 5 mg by mouth once a day. Your prescriber might raise your dose every 2 weeks up to a maximum of 40 mg a day depending on your response to the medication.

                          Your dose might be different if you have liver or kidney problems.

                          interactions

                          Interactions between Nebivolol (Bystolic) and other drugs

                          Nebivolol (Bystolic) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Nebivolol (Bystolic). Please note that only the generic name of each medication is listed below.

                          Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                          Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                          How much does Nebivolol (Bystolic) cost?

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                          contraindications-icon

                          Nebivolol (Bystolic) contraindications

                          Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Nebivolol (Bystolic) will not be safe for you to take.

                          • Extremely slow heart rate

                          • Heart problems (e.g., certain types of heart block, heart failure, cardiac shock, sick sinus syndrome without pacemaker)

                          • Severe liver problems

                          latest news

                          What is the latest news about Nebivolol (Bystolic)?

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                          images

                          Nebivolol (Bystolic) images

                          Purple Triangle B127 - Nebivolol 10mg Tablet
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                          References

                          Best studies we found

                          Acelajado, M.C., et al. (2012). Both morning and evening dosing of nebivolol reduces trough mean blood pressure surge in hypertensive patients. Journal of the American Society of Hypertension.

                          Fongemie, F., et al. (2015). A review of nebivolol pharmacology and clinical evidence. Drugs.

                          MedlinePlus. (2022). Sick sinus syndrome.

                          View All References (8)

                          Modavar Pharmaceuticals LLC. (2023). Nebivolol tablet [package insert]. DailyMed.

                          Morales, D. R., et al. (2017). Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: Population-based nested case control study. BMC Medicine.

                          Münzel, T., et al. (2009). Nebivolol: The somewhat-different β-adrenergic receptor blocker. Journal of the American College of Cardiology.

                          National Heart, Lung, and Blood Institute. (2022). What is cardiogenic shock?

                          Neutel, J. M., et al. (2010). Adding nebivolol to ongoing antihypertensive therapy improves blood pressure and response rates in patients with uncontrolled stage I-II hypertension. Journal of Human Hypertension.

                          Papademetriou, V. (2009). Comparison of nebivolol monotherapy versus nebivolol in combination with other antihypertensive therapies for the treatment of hypertension. The American Journal of Cardiology.

                          Vue, M. H., et al. (2011). Drug-induced glucose alterations part 1: Drug-induced hypoglycemia. DiabetesSpectrum.

                          Whelton, P. K., et al. (2018). 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: A report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines. Journal of the American College of Cardiology.

                          GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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