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Vyvanse vs. Strattera

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Vyvanse (lisdexamfetamine) and atomoxetine (Strattera) are both used to treat ADHD in adults and children age 6 years and older, but they have some key differences. Vyvanse is a stimulant and a controlled substance, meaning it has a high risk of misuse and dependency. Atomoxetine, on the other hand, is a non-stimulant and not a controlled substance, so it doesn't carry the same risk of addiction. However, it doesn’t improve ADHD symptoms as well as stimulant medications do. Vyvanse can also treat binge eating disorder in adults, while atomoxetine is only approved for ADHD. Vyvanse tends to work faster, often within a couple of hours, whereas atomoxetine may take a few weeks to show full effects. Additionally, Vyvanse is available in both capsule and chewable tablet forms, while atomoxetine is only available as capsules. Common side effects for Vyvanse include difficulty sleeping and loss of appetite, while atomoxetine can cause nausea and dry mouth. Both medications are available as low-cost generics.

Vyvanse

(lisdexamfetamine)

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Atomoxetine

(Strattera)

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Summary for Vyvanse

Prescription only

Vyvanse, the brand name for lisdexamfetamine, is a stimulant medication. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 6 years and older. It can also treat binge eating disorder (BED) in adults. Vyvanse (lisdexamfetamine) comes as capsules and chewable tablets. It's taken once per day in the morning. The dosage starts low and gets adjusted based on how you respond to the medication. Common side effects include trouble sleeping and loss of appetite. Vyvanse (lisdexamfetamine) is a controlled substance because it has a high risk of misuse and dependency.

Indications for Vyvanse

Pros and Cons for Vyvanse

Pros

  • A first-choice ADHD medication
  • Can help with ADHD for up to 14 hours with each dose
  • For binge eating disorder, can lower the number of binge-eating days per week by about one and a half days
  • Has a few options for people who have trouble swallowing pills whole (open the capsule or switch to chewable tablets)

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Might need to take gradually lower doses before stopping to avoid withdrawal symptoms
  • Not the best choice for people with heart conditions

Common Side Effects for Vyvanse

ADHD

Binge eating disorder

  • Dry mouth (36%)
  • Trouble sleeping (20%)

Warnings for Vyvanse

  • Risk of misuse and addiction
  • Risks to people with serious heart problems
  • Higher blood pressure and faster heart rate
  • Strange thoughts or behavior
  • Slow growth in children
  • Problems with blood flow in the arms and legs, including Raynaud's phenomenon
  • Serotonin syndrome

Summary for Strattera

Prescription only

Atomoxetine, also known by its brand name Strattera, is a non-stimulant medication. It's used to treat attention-deficit hyperactivity disorder (ADHD) in adults and children ages 6 years and up. Atomoxetine (Strattera) comes as capsules that are swallowed whole. You take your dosage either once or twice a day. Side effects are stomach upset and low appetite. It's not a controlled substance like some ADHD medications are. But atomoxetine (Strattera) still has a few serious risks like behavioral changes and heart problems.

Indications for Strattera

Pros and Cons for Strattera

Pros

  • A good non-stimulant option for both adults and children with ADHD
  • Can take with or without food
  • Not a controlled substance, so there isn't a risk of addiction and it doesn't have special rules when filling a prescription

Cons

Common Side Effects for Strattera

Adults:

  • Nausea (26%)
  • Dry mouth (20%)
  • Low appetite (16%)
  • Trouble sleeping (15%)
  • Feeling tired (10%)

Children:

  • Headache (19%)
  • Stomach pain (18%)
  • Low appetite (16%)
  • Sleepiness (11%)
  • Vomiting (11%)
  • Nausea (10%)

Warnings for Strattera

  • Risk of suicidal thoughts
  • Severe liver damage
  • Serious heart problems
  • Changes in blood pressure and heart rate
  • Aggressive behavior or other changes in behavior
  • Risk of mania in people with bipolar disorder
  • Long-lasting and painful erection
  • Slowed growth in children

Prices with our coupons for Vyvanse vs. Strattera

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Lisdexamfetamine30 capsules / 30mg
$67.96$389.37
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Atomoxetine30 capsules / 40mg
$28.28$77.26
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