Key takeaways
Vyvanse (lisdexamfetamine) and Adderall XR (dextroamphetamine / amphetamine salts) are both stimulant medications used to treat attention deficit-hyperactivity disorder (ADHD). They work by increasing levels of certain chemicals in the brain, such as norepinephrine, dopamine, and serotonin. However, Vyvanse is also FDA-approved for treating moderate-to-severe binge eating disorder (BED) in adults, while Adderall XR is not. Vyvanse is typically taken once per day in the morning, with a starting dose of 30 mg that can be gradually increased up to 70 mg. Adderall XR is also taken once daily, with starting doses varying by age and a maximum dosage of 30 mg for children and a recommended dosage of 20 mg per day for adults. Vyvanse is available in both capsule and chewable tablet forms, while Adderall XR is available as a capsule that can be opened and sprinkled on applesauce. Both medications have a risk of misuse and dependency and are controlled substances. Common side effects include difficulty sleeping, dry mouth, and loss of appetite. Both medications can interact with other drugs, especially those affecting serotonin levels, and may not be recommended if you have a history of heart problems.
