Key takeaways
Vyepti (eptinezumab) and Botox (onabotulinumtoxinA) are both used to prevent migraines, but they work in different ways and have different uses. Vyepti is a CGRP receptor blocker given as an IV infusion every 3 months, while Botox is a neuromuscular blocker injected into muscles every 3 months. Vyepti is only used for migraine prevention, whereas Botox is also used for various conditions like overactive bladder, muscle spasms, and excessive sweating. Vyepti's side effects are generally mild, such as common cold symptoms and itching, while Botox can cause more serious side effects like trouble breathing or swallowing if the toxin spreads. Additionally, both medications are only available as a brand name and require administration by a healthcare professional, but Vyepti involves a 30-minute infusion, whereas Botox injections are quicker, taking about 10 to 20 minutes.
