Vimovo vs. Duexis for Rheumatoid Arthritis and Osteoarthritis: Important Differences and Potential Risks.

Vimovo

(naproxen / esomeprazole)

Duexis

(ibuprofen / famotidine)

Summary for Vimovo

Prescription only

Vimovo (naproxen / esomeprazole) is a combination medication for people age 12 years and older who have arthritis. It contains naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that relieves arthritis symptoms like joint pain and swelling. This combination medication also contains the proton pump inhibitor (PPI) esomeprazole to protect against damage to the stomach from naproxen. Vimovo (naproxen / esomeprazole) is a tablet that's taken by mouth twice a day. Side effects can include inflammation of the stomach lining and diarrhea.

Indications for Vimovo

Treatment of different kinds of arthritis while lowering the risk for stomach ulcers
- Osteoarthritis (OA) in adults
- Rheumatoid arthritis (RA) in adults
- Ankylosing spondylitis (AS) in adults
- Arthritis in children 12 years and older (juvenile idiopathic arthritis, JIA)

Pros and Cons for Vimovo

Pros

Works well to relieve pain and swelling from arthritis
Helps protect against stomach irritation and ulcers from naproxen without needing to take another pill

Cons

Must take twice a day, each time at least 30 minutes before a meal
Has many serious risks from both naproxen and esomeprazole ingredients
Less flexible for dose adjustments since it's a fixed combination of two ingredients

Common Side Effects for Vimovo

Inflammation of the stomach lining, leading to symptoms like stomach pain, nausea, and loss of appetite (gastritis, 17%)
Diarrhea (6%)

Warnings for Vimovo

Heart attack or stroke
Stomach bleeding and ulcers
Liver damage
High blood pressure, heart failure, and fluid buildup in the body
Kidney damage
Severe allergic reaction or skin reaction
Abnormal nutrient and electrolyte levels
Bone fracture
Lupus
Harm to unborn baby

Summary for Duexis

Prescription only

Duexis is a prescription medication that contains ibuprofen (a non-steroidal anti-inflammatory drug (NSAID)) and famotidine (a H2 blocker). It's taken by adults to treat osteoarthritis (OA) and rheumatoid arthritis (RA), while also helps protect against stomach ulcer. This medication is taken by mouth three times per day. Side effects include headache, nausea, and high blood pressure. Brand name Duexis has been discontinued; this medication is only available as a generic.

Indications for Duexis

Treatment of osteoarthritis (OA) and rheumatoid arthritis (RA) in adults, while lowering the risk of stomach ulcers

Pros and Cons for Duexis

Pros

Taken by mouth
Famotidine helps protect against stomach ulcers
Can be stored at room temperature

Cons

Taken 3 times a day
Can't be crushed and doesn't come as a liquid; not a good choice for people who can't swallow tablets
Not safe for people with certain medical conditions, such as heart problems or kidney problems

Common Side Effects for Duexis

Nausea (6%)
Upset stomach or indigestion (5%)
Diarrhea (5%)
Constipation (4%)
Upper respiratory tract infection (4%)

Warnings for Duexis

Stomach bleeding and ulcers
Heart attack and stroke
High blood pressure, heart failure, and swelling
Kidney damage and high potassium levels
Liver problems
Severe allergic reactions
Harm to unborn babies
Accidentally taking too much medication
Changes in vision

Prices with our coupons for Vimovo vs. Duexis

Naproxen/Esomeprazole DR60 tablets / 500mg/20mg

$126.09$2,256.34

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Ibuprofen/Famotidine90 tablets / 800mg/26.6mg

$69.60$826.78

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Vimovo vs. Duexis

Vimovo

Duexis

Summary for Vimovo

Indications for Vimovo

Pros and Cons for Vimovo

Pros

Cons

Common Side Effects for Vimovo

Warnings for Vimovo

Summary for Duexis

Indications for Duexis

Pros and Cons for Duexis

Pros

Cons

Common Side Effects for Duexis

Warnings for Duexis

Prices with our coupons for Vimovo vs. Duexis

Compare other Rheumatoid Arthritis and Osteoarthritis drugs

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Vimovo

Duexis

Summary for Vimovo

Indications for Vimovo

Pros and Cons for Vimovo

Pros

Cons

Common Side Effects for Vimovo

Warnings for Vimovo

Summary for Duexis

Indications for Duexis

Pros and Cons for Duexis

Pros

Cons

Common Side Effects for Duexis

Warnings for Duexis