Key takeaways
Icosapent ethyl (Vascepa) and omega-3-acid ethyl esters (Lovaza) are both used to lower triglyceride levels in adults, but they have some key differences. Vascepa contains purified omega-3 fatty acids from fish oil and is taken twice daily with food. It is specifically used to lower the risk of heart problems in adults taking statins who have high triglyceride levels and heart disease or diabetes. Lovaza, on the other hand, contains two different omega-3 fatty acids, EPA and DHA, and can be taken once or twice daily with food. It is used as an add-on to diet for treating high triglycerides in adults with levels greater than 500 mg/dL. While both medications can cause side effects related to fish allergies and heart rhythm problems, Lovaza is also known to cause burping and changes in taste. Additionally, both medications are available as a lower-cost generic.
